Prospective Study of Treatment Outcomes and Long-Term Follow-Up in Patients with Cushings Syndrome

What this Trial Is About

Researchers are following participants with Cushings syndrome to collect data during their routine care and to create a registry for studying long-term outcomes. This observational study focuses on patients aged 14 and older with active or treated overt Cushings syndrome, mild adrenal Cushings syndrome MACS, or silent corticotroph tumors. The study is sponsored by Memorial Sloan Kettering Cancer Center and aims to gather information up to 10 years after various treatments. Participants undergo data collection before and over time after receiving surgical, medication, andor radiation therapies. Various questionnaires are used to assess quality of life, general health, anxiety, depression, stress, impulsivity, food cravings, and related symptoms. These tools include the Cushings QoL, Nottingham Health Profile, Hospital Anxiety and Depression Scale, Perceived Stress Scale, Barratts Impulsivity Scale, Beck Depression Inventory, State-Trait Anxiety Inventory, Food Craving Questionnaires, Visual Analogue Scale, and the STRAP-R food variant. During the study, participants will complete these questionnaires and provide ongoing data related to their condition and treatments. Researchers monitor outcomes up to 10 years following treatment, focusing on changes in health, quality of life, and psychological symptoms. This long-term observation helps improve understanding of Cushings syndrome outcomes under regular medical care.

Collecting Information About Treatment Results for Patients With Cushing's Syndrome