Actively Recruiting

Age: 18Years +
All Genders
NCT06287671

Colorectal Omics and OfCS Proteoglycans

Led by Claus Anders Bertelsen, PhD, MD · Updated on 2024-12-30

1000

Participants Needed

2

Research Sites

429 weeks

Total Duration

On this page

Sponsors

C

Claus Anders Bertelsen, PhD, MD

Lead Sponsor

V

Viborg Regional Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

This observational study aims to test proteomics, metabolomics and proteoglycans as predictors of postoperative complications after colorectal surgery and as biomarkers of colorectal cancer. The main questions to answer are: * can these biomarkers predict anastomotic leakages * can these biomarkers predict recurrence after colorectal cancer * can these biomarkers be used as diagnostic tests for colorectal cancer * can these biomarkers be identified in the tumor Participants will undergo elective colorectal resection or stoma closure.

CONDITIONS

Official Title

Colorectal Omics and OfCS Proteoglycans

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed or suspected of colorectal cancer or adenoma, inflammatory bowel disease, late complications from colon diverticulosis, colostomy reversal, or other conditions needing colorectal resection
  • Patients scheduled for elective surgical procedures coded KJFB20-KJFB99, KJFG30-37, or KJGB00-97 per Danish NOMESCO Classification
  • Able to speak Danish, English, or other languages with professional interpretation
  • Able to provide informed consent
Not Eligible

You will not qualify if you...

  • Patients undergoing synchronous liver resection, total gastrectomy or cardia resection, Whipple's procedure or major pancreatic resection, or total/partial nephrectomy or cystectomy (except pancreatic tail resection and metastasectomies)
  • Patients previously enrolled in the study
  • Patients known to be pregnant
  • Non-residents of Denmark

AI-Screening

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Trial Site Locations

Total: 2 locations

1

Nordsjaellands Hospital

Hillerød, Denmark, 3400

Actively Recruiting

2

Regionshospitalet Viborg

Viborg, Denmark, 8800

Not Yet Recruiting

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Research Team

N

Nanna B Hupfeld, ph.d.

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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