Study Comparing Early and Late Onset Colorectal Cancer Investigating Clinical, Socioeconomic, Genetic, and Molecular Factors Assessing Cancer Recurrence and Survival Outcomes

What this Trial Is About

Researchers are investigating the differences between Early Onset Colorectal Cancer EOCRC, which occurs before age 50, and Late Onset Colorectal Cancer LOCRC, diagnosed after age 50. EOCRC tends to be more aggressive and has a higher chance of cancer recurrence after surgery, even in early stages. The study aims to validate previous findings and explore how clinical, socioeconomic, behavioral, genetic, and molecular factors relate to cancer outcomes in these patients. Participants will be divided into two groups based on their age at diagnosis those 49 years old or younger EOCRC and those 50 years or older LOCRC. There is no intervention in this observational study instead, participants will complete questionnaires and provide samples to gather information on lifestyle, diet, genetics, and socioeconomic status. The study will follow patients for 24 months after surgery to monitor cancer recurrence and other outcomes. During the study, participants will complete questionnaires and provide biological samples. Researchers will collect data on cancer recurrence rates, lifestyle habits, genetic and molecular profiles, and socioeconomic factors. The primary measure is the rate of colorectal cancer recurrence 24 months after surgery. Secondary analyses will look at how lifestyle, genetics, molecular characteristics, and socioeconomic status relate to recurrence. The study is designed to better understand factors influencing colorectal cancer outcomes over a two-year period.

A Comparative Study Between Early Onset Colorectal Cancer and Late Onset Colorectal Cancer Patients