Actively Recruiting
Combination of Neurostimulation and Psychotherapy to Stop Worrying
Led by University Hospital, Ghent · Updated on 2026-03-12
85
Participants Needed
1
Research Sites
197 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study aims to investigate whether the combination of transcranial Direct Current Stimulation (tDCS) and cognitive-behavioral therapy (CBT) is more effective for treating repetitive negative thinking (RNT) in patients with the symptom of high rumination. High ruminators will be included (Group1, active tDCS-CBT group; Group2, sham tDCS-CBT group). All patients will receive active or sham tDCS.
CONDITIONS
Official Title
Combination of Neurostimulation and Psychotherapy to Stop Worrying
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 18 to 70 years
- Diagnosis of generalized anxiety disorder (GAD)
- Diagnosis of depressive disorder
- High rumination symptoms
- Willingness to participate in CBT and tDCS therapy sessions
You will not qualify if you...
- Other psychiatric disorders besides GAD or depression as assessed by a psychiatrist
- Abuse of alcohol, drugs, or medications not prescribed by a doctor
- No consent to participate in questionnaires or brain scans (fNIRS or EEG)
- Insufficient knowledge of Dutch language
- Acute or chronic suicidality
- Acute psychosis or manic depressive disorder
- Inability to commit to 8 CBT sessions or 4 weeks of tDCS therapy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
University Hospital Ghent
Ghent, East-Flanders, Belgium, 9000
Actively Recruiting
Research Team
C
Chris Baeken
CONTACT
S
Sara De Witte
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
TRIPLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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