Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Pelvic Bone Sarcomas to Assess Quality of Life and Disease Control

What this Trial Is About

Researchers are evaluating three treatment approachescarbon ion therapy, surgery with or without photonproton therapy, and proton therapy alonefor patients with pelvic bone sarcomas. The study aims to compare how these treatments affect disease control and quality of life, focusing on whether carbon ion therapy offers better patient-reported health outcomes and fewer side effects compared to surgery, as well as improved local control compared to proton therapy. Participants receive one of the three treatments and complete quality of life questionnaires at several points before any therapy, between 2 to 4 months, and again at 5 to 9 months after treatment completion, followed by annual assessments for up to five years. Researchers also review patients medical records to gather detailed clinical data. This observational study involves collecting patient-reported outcomes and medical information without assigning treatments. Throughout the study, patients are asked to complete questionnaires taking about 20 minutes to assess their health-related quality of life. These assessments occur at baseline and various follow-up points up to five years after treatment. Researchers monitor disease progression, local control of the sarcoma, survival outcomes, and treatment-related toxicities. The studys follow-up and data collection span several years to better understand long-term effects and outcomes of the different treatment approaches.

Comparing Carbon Ion Therapy, Surgery, and Proton Therapy for Management of Pelvic Sarcomas Involving the Bone