Epidemiology and Disease Burden of Lateral Epicondylitis in the USA: Analysis of 85,318 Patients.
Ryan M Degen, Matthew S Conti, Christopher L Camp...
https://pubmed.ncbi.nlm.nih.gov/29398988/Actively Recruiting
Led by University of Vermont · Updated on 2026-02-04
68
Participants Needed
1
Research Sites
N/A
Total Duration
Lateral elbow pain, often referred to as lateral elbow tendinopathy or tennis elbow, can greatly limit daily activities. This research compares two treatment approaches to see which might better help people with this condition. The study involves adults referred for lateral elbow pain and evaluates if the Think in Nerve Length and Layers TINLL method is more effective than traditional therapy techniques. Participants are assigned to one of two groups based on their previous treatments a traditional treatment group or a TINLL group. The traditional group receives weekly treatments for 4 to 6 weeks, including wrist extensor stretching and strengthening, soft tissue work, joint mobilization, taping, ergonomic advice, electrical nerve stimulation, and wrist splinting. The TINLL group has treatments every 1 to 2 weeks over 4 to 6 weeks, focusing on joint and tendon mobilization, elastic taping of muscles and nerves, stretching and strengthening of elbow and upper arm muscles, and ergonomic strategies. After one month, participants may choose to switch groups if they wish. Participants undergo assessments before treatment, at 2 weeks, 4 weeks, and at the end of treatment. These include pain rating scales, grip strength tests, pinch strength tests, and functional surveys common for elbow pain. Six months after treatment, follow-up calls assess pain, function, and use of taping or home exercises. The study monitors changes over time to understand how each treatment impacts pain and function in lateral elbow tendinopathy.
CONDITIONS
Comparing the Effectiveness of the 'Think in Nerve Length and Layers' (TINLL) Approach to Traditional Treatment for Patients With Lateral Elbow Pain.
V
Victoria Priganc, PhD
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University of Vermont
Lead Sponsor
This table compares participation in this trial with other options available for this condition. The information is drawn from published research and the trial’s study details and is provided for educational purposes only.
| Factors | TINLL (Think in Nerve Length and Layers) radial nerve approach | Traditional muscle stretching and strengthening |
|---|---|---|
| What it is | A manual therapy approach addressing radial nerve tension using the 'Think in Nerve Length and Layers' (TINLL) concept, involving nerve-focused techniques to relieve symptoms of lateral elbow pain. | A standard physiotherapy approach using traditional stretching and strengthening exercises focused on forearm and wrist muscles to improve lateral elbow function and reduce pain. |
| Primary use or rationale | Targets neurodynamic dysfunction by focusing therapy on radial nerve mobility and symptom relief, addressing nerve involvement believed to contribute to lateral elbow pain. | Aims to restore function and reduce pain by strengthening and stretching forearm muscles, addressing mechanical overuse and muscular causes of lateral elbow pain. |
| How it is given or performed | Provided once per week for 4 to 6 weeks, unless the participant improves sooner; includes manual techniques focused specifically on the radial nerve. | Delivered once per week for 4 to 6 weeks (or less if improvement occurs) using standard exercise routines focused on forearm and wrist muscle groups. |
| Evidence status | Currently being studied in this clinical trial; published evidence is limited and largely conceptual or based on small studies regarding nerve-focused approaches in elbow pain. | Considered a standard and well-supported approach for lateral elbow tendinopathy, with efficacy supported by multiple reviews and clinical guidelines. |
| Important limitations | Lack of large-scale published clinical evidence; the effectiveness and long-term outcomes of nerve-focused TINLL techniques are not established and may differ between patient subgroups. | While well established, traditional muscle approaches may not address symptoms in all patients, particularly if nerve involvement is present; some may have incomplete response. |
Disclaimer: This comparison is created with the help of artificial intelligence(AI) and may contain errors or missing information. It is not medical advice and does not mean one option is better or safer than another. Clinical trials are still being studied, and joining a trial is your choice. Please consult your healthcare professional before making any decisions.
You may qualify if you...
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 4 to 6 weeks
Participants receive either the TINLL or traditional treatment for lateral elbow pain. Treatments occur once every 1-2 weeks for the TINLL group or once weekly for the traditional group over 4 to 6 weeks. Assessments are conducted at the initial visit, 2-week visit, and 4-week visit to measure pain, function, and strength.
3 visits (in-person) at initial, 2-week, and 4-week
Duration - 6 months after treatment
Six months after treatment, participants are contacted by phone to answer follow-up questions about pain, function, and use of taping and home exercises.
1 phone call
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NON_RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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Ryan M Degen, Matthew S Conti, Christopher L Camp...
https://pubmed.ncbi.nlm.nih.gov/29398988/Alison Taylor, Aviva L Wolff
https://pubmed.ncbi.nlm.nih.gov/34193382/Ann M Lucado, Joseph M Day, Joshua I Vincent...
https://pubmed.ncbi.nlm.nih.gov/36453071/University of Vermont
Lead Sponsor