Actively Recruiting
Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial
Led by SWOG Cancer Research Network · Updated on 2025-09-09
364
Participants Needed
387
Research Sites
642 weeks
Total Duration
On this page
Sponsors
S
SWOG Cancer Research Network
Lead Sponsor
N
National Cancer Institute (NCI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This phase III trial compares the effect of adding surgery to a standard of care immunotherapy-based drug combination versus a standard of care immunotherapy-based drug combination alone in treating patients with kidney cancer that has spread to other places in the body (metastatic). Immunotherapy with monoclonal antibodies, such as nivolumab, ipilimumab, pembrolizumab, and avelumab, may help the body's immune system attack the cancer, and may interfere with the ability of tumor cells to grow and spread. Axitinib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth. Surgery to remove the kidney, called a nephrectomy, is also considered standard of care; however, doctors who treat kidney cancer do not agree on its benefits. It is not yet known if the addition of surgery to an immunotherapy-based drug combination works better than an immunotherapy-based drug combination alone in treating patients with kidney cancer.
CONDITIONS
Official Title
Comparing the Outcome of Immunotherapy-Based Drug Combination Therapy With or Without Surgery to Remove the Kidney in Metastatic Kidney Cancer, the PROBE Trial
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Diagnosis of clear cell or non-clear cell renal cell carcinoma confirmed by tissue sample
- Presence of primary kidney tumor
- Evidence of metastatic kidney cancer confirmed by chest and abdomen/pelvis scans within 90 days before registration or treatment
- For Step 2 randomization, stable disease or partial response after 12 weeks of pre-randomization treatment
- At least two infusions of nivolumab + one of ipilimumab, or two infusions of pembrolizumab, or two infusions of avelumab received prior to randomization
- Planned surgery date within 42 days of randomization (for Step 2)
- Suitable candidate for surgery as determined by a study urologist
- Zubrod performance status of 0-1
- Normal liver and kidney function tests within 28 days prior to randomization
- Willing to provide specimens for research and able to provide informed consent
You will not qualify if you...
- Known active brain metastases or neurological symptoms from brain metastases
- More than allowed prior systemic therapy for metastatic kidney cancer beyond protocol limits
- Prior immunotherapy within one year before study registration or pre-randomization treatment
- Solitary or transplanted kidney
- Other recent or current malignancies except certain treated skin or early-stage cancers
- Medical conditions preventing safe use of immunotherapy or nephrectomy
- Tumor progression in primary site after pre-randomization treatment
- For Step 2, must not have progression in primary tumor
- Brain imaging if done must show no active disease
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 387 locations
1
University of Alabama at Birmingham Cancer Center
Birmingham, Alabama, United States, 35233
Actively Recruiting
2
Banner MD Anderson Cancer Center
Gilbert, Arizona, United States, 85234
Actively Recruiting
3
Kingman Regional Medical Center
Kingman, Arizona, United States, 86401
Actively Recruiting
4
Banner University Medical Center - Tucson
Tucson, Arizona, United States, 85719
Actively Recruiting
5
University of Arizona Cancer Center-North Campus
Tucson, Arizona, United States, 85719
Actively Recruiting
6
Mercy Hospital Fort Smith
Fort Smith, Arkansas, United States, 72903
Actively Recruiting
7
PCR Oncology
Arroyo Grande, California, United States, 93420
Actively Recruiting
8
Sutter Auburn Faith Hospital
Auburn, California, United States, 95602
Actively Recruiting
9
Sutter Cancer Centers Radiation Oncology Services-Auburn
Auburn, California, United States, 95603
Actively Recruiting
10
Alta Bates Summit Medical Center-Herrick Campus
Berkeley, California, United States, 94704
Actively Recruiting
11
Keck Medicine of USC Buena Park
Buena Park, California, United States, 90621
Actively Recruiting
12
Sutter Cancer Centers Radiation Oncology Services-Cameron Park
Cameron Park, California, United States, 95682
Actively Recruiting
13
Eden Hospital Medical Center
Castro Valley, California, United States, 94546
Actively Recruiting
14
Sutter Davis Hospital
Davis, California, United States, 95616
Actively Recruiting
15
City of Hope Comprehensive Cancer Center
Duarte, California, United States, 91010
Actively Recruiting
16
Palo Alto Medical Foundation-Fremont
Fremont, California, United States, 94538
Actively Recruiting
17
Keck Medicine of USC Huntington Beach
Huntington Beach, California, United States, 92648
Actively Recruiting
18
Keck Medicine of USC Koreatown
Los Angeles, California, United States, 90020
Actively Recruiting
19
Los Angeles County-USC Medical Center
Los Angeles, California, United States, 90033
Actively Recruiting
20
USC / Norris Comprehensive Cancer Center
Los Angeles, California, United States, 90033
Actively Recruiting
21
Cedars Sinai Medical Center
Los Angeles, California, United States, 90048
Actively Recruiting
22
UCLA / Jonsson Comprehensive Cancer Center
Los Angeles, California, United States, 90095
Actively Recruiting
23
Memorial Medical Center
Modesto, California, United States, 95355
Actively Recruiting
24
Palo Alto Medical Foundation-Camino Division
Mountain View, California, United States, 94040
Actively Recruiting
25
Palo Alto Medical Foundation-Gynecologic Oncology
Mountain View, California, United States, 94040
Actively Recruiting
26
USC Norris Oncology/Hematology-Newport Beach
Newport Beach, California, United States, 92663
Actively Recruiting
27
Sutter Cancer Research Consortium
Novato, California, United States, 94945
Actively Recruiting
28
Palo Alto Medical Foundation Health Care
Palo Alto, California, United States, 94301
Actively Recruiting
29
Keck Medical Center of USC Pasadena
Pasadena, California, United States, 91105
Actively Recruiting
30
Sutter Cancer Centers Radiation Oncology Services-Roseville
Roseville, California, United States, 95661
Actively Recruiting
31
Sutter Roseville Medical Center
Roseville, California, United States, 95661
Actively Recruiting
32
Sutter Medical Center Sacramento
Sacramento, California, United States, 95816
Actively Recruiting
33
University of California Davis Comprehensive Cancer Center
Sacramento, California, United States, 95817
Actively Recruiting
34
California Pacific Medical Center-Pacific Campus
San Francisco, California, United States, 94115
Actively Recruiting
35
Mills Health Center
San Mateo, California, United States, 94401
Actively Recruiting
36
Palo Alto Medical Foundation-Santa Cruz
Santa Cruz, California, United States, 95065
Actively Recruiting
37
Sutter Pacific Medical Foundation
Santa Rosa, California, United States, 95403
Actively Recruiting
38
City of Hope South Pasadena
South Pasadena, California, United States, 91030
Actively Recruiting
39
Palo Alto Medical Foundation-Sunnyvale
Sunnyvale, California, United States, 94086
Actively Recruiting
40
Cedars-Sinai Cancer - Tarzana
Tarzana, California, United States, 91356
Actively Recruiting
41
City of Hope Upland
Upland, California, United States, 91786
Actively Recruiting
42
Sutter Cancer Centers Radiation Oncology Services-Vacaville
Vacaville, California, United States, 95687
Actively Recruiting
43
Sutter Solano Medical Center/Cancer Center
Vallejo, California, United States, 94589
Actively Recruiting
44
MedStar Washington Hospital Center
Washington D.C., District of Columbia, United States, 20010
Actively Recruiting
45
AdventHealth Altamonte
Altamonte Springs, Florida, United States, 32701
Actively Recruiting
46
AdventHealth Celebration
Celebration, Florida, United States, 34747
Actively Recruiting
47
AdventHealth Kissimmee
Kissimmee, Florida, United States, 34744
Actively Recruiting
48
AdventHealth Medical Group Urology at Orlando
Orlando, Florida, United States, 32803
Actively Recruiting
49
AdventHealth Orlando
Orlando, Florida, United States, 32803
Actively Recruiting
50
Orlando Health Cancer Institute
Orlando, Florida, United States, 32806
Actively Recruiting
51
AdventHealth East Orlando
Orlando, Florida, United States, 32822
Actively Recruiting
52
AdventHealth Winter Park
Winter Park, Florida, United States, 32792
Actively Recruiting
53
Saint Anthony's Health
Alton, Illinois, United States, 62002
Actively Recruiting
54
Rush - Copley Medical Center
Aurora, Illinois, United States, 60504
Actively Recruiting
55
Advocate Good Shepherd Hospital
Barrington, Illinois, United States, 60010
Actively Recruiting
56
Illinois CancerCare-Bloomington
Bloomington, Illinois, United States, 61704
Actively Recruiting
57
Loyola Center for Health at Burr Ridge
Burr Ridge, Illinois, United States, 60527
Actively Recruiting
58
Illinois CancerCare-Canton
Canton, Illinois, United States, 61520
Actively Recruiting
59
Memorial Hospital of Carbondale
Carbondale, Illinois, United States, 62902
Actively Recruiting
60
SIH Cancer Institute
Carterville, Illinois, United States, 62918
Actively Recruiting
61
Illinois CancerCare-Carthage
Carthage, Illinois, United States, 62321
Actively Recruiting
62
Centralia Oncology Clinic
Centralia, Illinois, United States, 62801
Actively Recruiting
63
Saint Mary's Hospital
Centralia, Illinois, United States, 62801
Actively Recruiting
64
Northwestern University
Chicago, Illinois, United States, 60611
Actively Recruiting
65
Rush University Medical Center
Chicago, Illinois, United States, 60612
Actively Recruiting
66
University of Illinois
Chicago, Illinois, United States, 60612
Actively Recruiting
67
University of Chicago Comprehensive Cancer Center
Chicago, Illinois, United States, 60637
Active, Not Recruiting
68
Advocate Illinois Masonic Medical Center
Chicago, Illinois, United States, 60657
Actively Recruiting
69
AMG Crystal Lake - Oncology
Crystal Lake, Illinois, United States, 60014
Actively Recruiting
70
Carle at The Riverfront
Danville, Illinois, United States, 61832
Actively Recruiting
71
Cancer Care Specialists of Illinois - Decatur
Decatur, Illinois, United States, 62526
Actively Recruiting
72
Decatur Memorial Hospital
Decatur, Illinois, United States, 62526
Actively Recruiting
73
Northwestern Medicine Cancer Center Kishwaukee
DeKalb, Illinois, United States, 60115
Actively Recruiting
74
Illinois CancerCare-Dixon
Dixon, Illinois, United States, 61021
Actively Recruiting
75
Advocate Good Samaritan Hospital
Downers Grove, Illinois, United States, 60515
Actively Recruiting
76
Carle Physician Group-Effingham
Effingham, Illinois, United States, 62401
Actively Recruiting
77
Crossroads Cancer Center
Effingham, Illinois, United States, 62401
Actively Recruiting
78
Advocate Sherman Hospital
Elgin, Illinois, United States, 60123
Actively Recruiting
79
Elmhurst Memorial Hospital
Elmhurst, Illinois, United States, 60126
Actively Recruiting
80
Illinois CancerCare-Eureka
Eureka, Illinois, United States, 61530
Actively Recruiting
81
Illinois CancerCare-Galesburg
Galesburg, Illinois, United States, 61401
Actively Recruiting
82
Western Illinois Cancer Treatment Center
Galesburg, Illinois, United States, 61401
Actively Recruiting
83
Northwestern Medicine Cancer Center Delnor
Geneva, Illinois, United States, 60134
Actively Recruiting
84
Advocate South Suburban Hospital
Hazel Crest, Illinois, United States, 60429
Actively Recruiting
85
Loyola Medicine Homer Glen
Homer Glen, Illinois, United States, 60491
Actively Recruiting
86
Illinois CancerCare-Kewanee Clinic
Kewanee, Illinois, United States, 61443
Actively Recruiting
87
Northwestern Medicine Lake Forest Hospital
Lake Forest, Illinois, United States, 60045
Actively Recruiting
88
AMG Libertyville - Oncology
Libertyville, Illinois, United States, 60048
Actively Recruiting
89
Condell Memorial Hospital
Libertyville, Illinois, United States, 60048
Actively Recruiting
90
Illinois CancerCare-Macomb
Macomb, Illinois, United States, 61455
Actively Recruiting
91
Carle Physician Group-Mattoon/Charleston
Mattoon, Illinois, United States, 61938
Actively Recruiting
92
Loyola University Medical Center
Maywood, Illinois, United States, 60153
Actively Recruiting
93
Marjorie Weinberg Cancer Center at Loyola-Gottlieb
Melrose Park, Illinois, United States, 60160
Actively Recruiting
94
Good Samaritan Regional Health Center
Mount Vernon, Illinois, United States, 62864
Actively Recruiting
95
Edward Hospital/Cancer Center
Naperville, Illinois, United States, 60540
Actively Recruiting
96
UC Comprehensive Cancer Center at Silver Cross
New Lenox, Illinois, United States, 60451
Active, Not Recruiting
97
Cancer Care Center of O'Fallon
O'Fallon, Illinois, United States, 62269
Actively Recruiting
98
Advocate Christ Medical Center
Oak Lawn, Illinois, United States, 60453-2699
Actively Recruiting
99
University of Chicago Medicine-Orland Park
Orland Park, Illinois, United States, 60462
Active, Not Recruiting
100
Illinois CancerCare-Ottawa Clinic
Ottawa, Illinois, United States, 61350
Actively Recruiting
101
Advocate Lutheran General Hospital
Park Ridge, Illinois, United States, 60068
Actively Recruiting
102
Illinois CancerCare-Pekin
Pekin, Illinois, United States, 61554
Actively Recruiting
103
Illinois CancerCare-Peoria
Peoria, Illinois, United States, 61615
Actively Recruiting
104
Methodist Medical Center of Illinois
Peoria, Illinois, United States, 61636
Actively Recruiting
105
Illinois CancerCare-Peru
Peru, Illinois, United States, 61354
Actively Recruiting
106
Valley Radiation Oncology
Peru, Illinois, United States, 61354
Actively Recruiting
107
Edward Hospital/Cancer Center?Plainfield
Plainfield, Illinois, United States, 60585
Actively Recruiting
108
Illinois CancerCare-Princeton
Princeton, Illinois, United States, 61356
Actively Recruiting
109
Southern Illinois University School of Medicine
Springfield, Illinois, United States, 62702
Actively Recruiting
110
Springfield Clinic
Springfield, Illinois, United States, 62702
Actively Recruiting
111
Memorial Medical Center
Springfield, Illinois, United States, 62781
Actively Recruiting
112
Carle Cancer Center
Urbana, Illinois, United States, 61801
Actively Recruiting
113
The Carle Foundation Hospital
Urbana, Illinois, United States, 61801
Actively Recruiting
114
Northwestern Medicine Cancer Center Warrenville
Warrenville, Illinois, United States, 60555
Actively Recruiting
115
Illinois CancerCare - Washington
Washington, Illinois, United States, 61571
Actively Recruiting
116
Rush-Copley Healthcare Center
Yorkville, Illinois, United States, 60560
Actively Recruiting
117
Reid Health
Richmond, Indiana, United States, 47374
Actively Recruiting
118
Mary Greeley Medical Center
Ames, Iowa, United States, 50010
Actively Recruiting
119
McFarland Clinic - Ames
Ames, Iowa, United States, 50010
Actively Recruiting
120
McFarland Clinic - Boone
Boone, Iowa, United States, 50036
Actively Recruiting
121
Saint Anthony Regional Hospital
Carroll, Iowa, United States, 51401
Active, Not Recruiting
122
Iowa Methodist Medical Center
Des Moines, Iowa, United States, 50309
Active, Not Recruiting
123
Medical Oncology and Hematology Associates-Des Moines
Des Moines, Iowa, United States, 50309
Active, Not Recruiting
124
Broadlawns Medical Center
Des Moines, Iowa, United States, 50314
Active, Not Recruiting
125
Iowa Lutheran Hospital
Des Moines, Iowa, United States, 50316
Active, Not Recruiting
126
McFarland Clinic - Trinity Cancer Center
Fort Dodge, Iowa, United States, 50501
Actively Recruiting
127
Trinity Regional Medical Center
Fort Dodge, Iowa, United States, 50501
Active, Not Recruiting
128
McFarland Clinic - Jefferson
Jefferson, Iowa, United States, 50129
Actively Recruiting
129
McFarland Clinic - Marshalltown
Marshalltown, Iowa, United States, 50158
Actively Recruiting
130
Methodist West Hospital
West Des Moines, Iowa, United States, 50266-7700
Active, Not Recruiting
131
Central Care Cancer Center - Garden City
Garden City, Kansas, United States, 67846
Actively Recruiting
132
Central Care Cancer Center - Great Bend
Great Bend, Kansas, United States, 67530
Actively Recruiting
133
University of Kentucky/Markey Cancer Center
Lexington, Kentucky, United States, 40536
Actively Recruiting
134
Hematology/Oncology Clinic PLLC
Baton Rouge, Louisiana, United States, 70809
Suspended
135
East Jefferson General Hospital
Metairie, Louisiana, United States, 70006
Actively Recruiting
136
LSU Healthcare Network / Metairie Multi-Specialty Clinic
Metairie, Louisiana, United States, 70006
Actively Recruiting
137
Louisiana State University Health Science Center
New Orleans, Louisiana, United States, 70112
Actively Recruiting
138
Tulane University Health Sciences Center
New Orleans, Louisiana, United States, 70112
Actively Recruiting
139
University Medical Center New Orleans
New Orleans, Louisiana, United States, 70112
Actively Recruiting
140
University of Michigan Comprehensive Cancer Center
Ann Arbor, Michigan, United States, 48109
Actively Recruiting
141
Bronson Battle Creek
Battle Creek, Michigan, United States, 49017
Actively Recruiting
142
University of Michigan - Brighton Center for Specialty Care
Brighton, Michigan, United States, 48116
Actively Recruiting
143
Henry Ford Cancer Institute-Downriver
Brownstown, Michigan, United States, 48183
Active, Not Recruiting
144
Henry Ford Hematology Oncology - Hayes
Clinton Township, Michigan, United States, 48038
Active, Not Recruiting
145
Henry Ford Macomb Hospital-Clinton Township
Clinton Township, Michigan, United States, 48038
Active, Not Recruiting
146
Henry Ford Medical Center-Fairlane
Dearborn, Michigan, United States, 48126
Active, Not Recruiting
147
Henry Ford Hospital
Detroit, Michigan, United States, 48202
Active, Not Recruiting
148
Helen DeVos Children's Hospital at Spectrum Health
Grand Rapids, Michigan, United States, 49503
Actively Recruiting
149
Spectrum Health at Butterworth Campus
Grand Rapids, Michigan, United States, 49503
Actively Recruiting
150
Trinity Health Grand Rapids Hospital
Grand Rapids, Michigan, United States, 49503
Actively Recruiting
151
Allegiance Health
Jackson, Michigan, United States, 49201
Active, Not Recruiting
152
Bronson Methodist Hospital
Kalamazoo, Michigan, United States, 49007
Actively Recruiting
153
West Michigan Cancer Center
Kalamazoo, Michigan, United States, 49007
Actively Recruiting
154
Ascension Borgess Cancer Center
Kalamazoo, Michigan, United States, 49009
Actively Recruiting
155
Borgess Medical Center
Kalamazoo, Michigan, United States, 49048
Actively Recruiting
156
Trinity Health Muskegon Hospital
Muskegon, Michigan, United States, 49444
Actively Recruiting
157
Lakeland Hospital Niles
Niles, Michigan, United States, 49120
Actively Recruiting
158
Cancer and Hematology Centers of Western Michigan - Norton Shores
Norton Shores, Michigan, United States, 49444
Actively Recruiting
159
Henry Ford Medical Center-Columbus
Novi, Michigan, United States, 48377
Active, Not Recruiting
160
Spectrum Health Reed City Hospital
Reed City, Michigan, United States, 49677
Actively Recruiting
161
Lakeland Medical Center Saint Joseph
Saint Joseph, Michigan, United States, 49085
Actively Recruiting
162
Marie Yeager Cancer Center
Saint Joseph, Michigan, United States, 49085
Actively Recruiting
163
Henry Ford Macomb Health Center - Shelby Township
Shelby, Michigan, United States, 48315
Suspended
164
Munson Medical Center
Traverse City, Michigan, United States, 49684
Actively Recruiting
165
Henry Ford West Bloomfield Hospital
West Bloomfield, Michigan, United States, 48322
Active, Not Recruiting
166
Henry Ford Wyandotte Hospital
Wyandotte, Michigan, United States, 48192
Active, Not Recruiting
167
University of Michigan Health - West
Wyoming, Michigan, United States, 49519
Actively Recruiting
168
Fairview Ridges Hospital
Burnsville, Minnesota, United States, 55337
Suspended
169
Minnesota Oncology - Burnsville
Burnsville, Minnesota, United States, 55337
Actively Recruiting
170
Cambridge Medical Center
Cambridge, Minnesota, United States, 55008
Actively Recruiting
171
Mercy Hospital
Coon Rapids, Minnesota, United States, 55433
Actively Recruiting
172
Fairview Southdale Hospital
Edina, Minnesota, United States, 55435
Actively Recruiting
173
Unity Hospital
Fridley, Minnesota, United States, 55432
Actively Recruiting
174
Fairview Clinics and Surgery Center Maple Grove
Maple Grove, Minnesota, United States, 55369
Actively Recruiting
175
Minnesota Oncology Hematology PA-Maplewood
Maplewood, Minnesota, United States, 55109
Actively Recruiting
176
Saint John's Hospital - Healtheast
Maplewood, Minnesota, United States, 55109
Actively Recruiting
177
Abbott-Northwestern Hospital
Minneapolis, Minnesota, United States, 55407
Actively Recruiting
178
Hennepin County Medical Center
Minneapolis, Minnesota, United States, 55415
Actively Recruiting
179
Health Partners Inc
Minneapolis, Minnesota, United States, 55454
Actively Recruiting
180
Monticello Cancer Center
Monticello, Minnesota, United States, 55362
Actively Recruiting
181
New Ulm Medical Center
New Ulm, Minnesota, United States, 56073
Actively Recruiting
182
Fairview Northland Medical Center
Princeton, Minnesota, United States, 55371
Actively Recruiting
183
North Memorial Medical Health Center
Robbinsdale, Minnesota, United States, 55422
Actively Recruiting
184
Park Nicollet Clinic - Saint Louis Park
Saint Louis Park, Minnesota, United States, 55416
Actively Recruiting
185
Regions Hospital
Saint Paul, Minnesota, United States, 55101
Actively Recruiting
186
United Hospital
Saint Paul, Minnesota, United States, 55102
Actively Recruiting
187
Saint Francis Regional Medical Center
Shakopee, Minnesota, United States, 55379
Actively Recruiting
188
Lakeview Hospital
Stillwater, Minnesota, United States, 55082
Actively Recruiting
189
Ridgeview Medical Center
Waconia, Minnesota, United States, 55387
Actively Recruiting
190
Rice Memorial Hospital
Willmar, Minnesota, United States, 56201
Actively Recruiting
191
Minnesota Oncology Hematology PA-Woodbury
Woodbury, Minnesota, United States, 55125
Actively Recruiting
192
Fairview Lakes Medical Center
Wyoming, Minnesota, United States, 55092
Actively Recruiting
193
Gulfport Memorial Hospital
Gulfport, Mississippi, United States, 39502
Actively Recruiting
194
Saint Louis Cancer and Breast Institute-Ballwin
Ballwin, Missouri, United States, 63011
Actively Recruiting
195
Central Care Cancer Center - Bolivar
Bolivar, Missouri, United States, 65613
Actively Recruiting
196
Cox Cancer Center Branson
Branson, Missouri, United States, 65616
Actively Recruiting
197
Saint Francis Medical Center
Cape Girardeau, Missouri, United States, 63703
Actively Recruiting
198
Southeast Cancer Center
Cape Girardeau, Missouri, United States, 63703
Actively Recruiting
199
Parkland Health Center - Farmington
Farmington, Missouri, United States, 63640
Actively Recruiting
200
Capital Region Southwest Campus
Jefferson City, Missouri, United States, 65109
Actively Recruiting
201
Freeman Health System
Joplin, Missouri, United States, 64804
Actively Recruiting
202
Mercy Hospital Joplin
Joplin, Missouri, United States, 64804
Actively Recruiting
203
Delbert Day Cancer Institute at PCRMC
Rolla, Missouri, United States, 65401
Actively Recruiting
204
Mercy Clinic-Rolla-Cancer and Hematology
Rolla, Missouri, United States, 65401
Actively Recruiting
205
Heartland Regional Medical Center
Saint Joseph, Missouri, United States, 64506
Actively Recruiting
206
Sainte Genevieve County Memorial Hospital
Sainte Genevieve, Missouri, United States, 63670
Actively Recruiting
207
Mercy Hospital Springfield
Springfield, Missouri, United States, 65804
Actively Recruiting
208
CoxHealth South Hospital
Springfield, Missouri, United States, 65807
Actively Recruiting
209
Saint Louis Cancer and Breast Institute-South City
St Louis, Missouri, United States, 63109
Actively Recruiting
210
Mercy Hospital South
St Louis, Missouri, United States, 63128
Actively Recruiting
211
Missouri Baptist Medical Center
St Louis, Missouri, United States, 63131
Actively Recruiting
212
Mercy Hospital Saint Louis
St Louis, Missouri, United States, 63141
Actively Recruiting
213
Missouri Baptist Sullivan Hospital
Sullivan, Missouri, United States, 63080
Actively Recruiting
214
Missouri Baptist Outpatient Center-Sunset Hills
Sunset Hills, Missouri, United States, 63127
Actively Recruiting
215
Mercy Hospital Washington
Washington, Missouri, United States, 63090
Actively Recruiting
216
Nebraska Cancer Specialists/Oncology Hematology West PC - MECC
Omaha, Nebraska, United States, 68114
Actively Recruiting
217
Nebraska Methodist Hospital
Omaha, Nebraska, United States, 68114
Actively Recruiting
218
Oncology Associates PC
Omaha, Nebraska, United States, 68114
Actively Recruiting
219
Carson Tahoe Regional Medical Center
Carson City, Nevada, United States, 89703
Actively Recruiting
220
Cancer and Blood Specialists-Henderson
Henderson, Nevada, United States, 89052
Actively Recruiting
221
Comprehensive Cancer Centers of Nevada - Henderson
Henderson, Nevada, United States, 89052
Actively Recruiting
222
Comprehensive Cancer Centers of Nevada-Horizon Ridge
Henderson, Nevada, United States, 89052
Actively Recruiting
223
Las Vegas Cancer Center-Henderson
Henderson, Nevada, United States, 89052
Suspended
224
OptumCare Cancer Care at Seven Hills
Henderson, Nevada, United States, 89052
Actively Recruiting
225
Comprehensive Cancer Centers of Nevada-Southeast Henderson
Henderson, Nevada, United States, 89074
Actively Recruiting
226
GenesisCare USA - Henderson
Henderson, Nevada, United States, 89074
Actively Recruiting
227
Las Vegas Urology - Green Valley
Henderson, Nevada, United States, 89074
Actively Recruiting
228
Las Vegas Urology - Pebble
Henderson, Nevada, United States, 89074
Actively Recruiting
229
Urology Specialists of Nevada - Green Valley
Henderson, Nevada, United States, 89074
Actively Recruiting
230
Las Vegas Urology - Pecos
Las Vegas, Nevada, United States, 89074
Actively Recruiting
231
Desert West Surgery
Las Vegas, Nevada, United States, 89102
Suspended
232
OptumCare Cancer Care at Charleston
Las Vegas, Nevada, United States, 89102
Actively Recruiting
233
University Medical Center of Southern Nevada
Las Vegas, Nevada, United States, 89102
Actively Recruiting
234
Hope Cancer Care of Nevada
Las Vegas, Nevada, United States, 89103
Actively Recruiting
235
Radiation Oncology Centers of Nevada Central
Las Vegas, Nevada, United States, 89106
Actively Recruiting
236
Urology Specialists of Nevada - Central
Las Vegas, Nevada, United States, 89106
Actively Recruiting
237
GenesisCare USA - Las Vegas
Las Vegas, Nevada, United States, 89109
Actively Recruiting
238
Sunrise Hospital and Medical Center
Las Vegas, Nevada, United States, 89109
Actively Recruiting
239
Las Vegas Prostate Cancer Center
Las Vegas, Nevada, United States, 89113
Actively Recruiting
240
Las Vegas Urology - Sunset
Las Vegas, Nevada, United States, 89113
Actively Recruiting
241
Urology Specialists of Nevada - Southwest
Las Vegas, Nevada, United States, 89113
Actively Recruiting
242
Radiation Oncology Centers of Nevada Southeast
Las Vegas, Nevada, United States, 89119
Actively Recruiting
243
Ann M Wierman MD LTD
Las Vegas, Nevada, United States, 89128
Actively Recruiting
244
Comprehensive Cancer Centers of Nevada - Northwest
Las Vegas, Nevada, United States, 89128
Actively Recruiting
245
GenesisCare USA - Vegas Tenaya
Las Vegas, Nevada, United States, 89128
Actively Recruiting
246
Las Vegas Urology - Cathedral Rock
Las Vegas, Nevada, United States, 89128
Actively Recruiting
247
Las Vegas Urology - Smoke Ranch
Las Vegas, Nevada, United States, 89128
Actively Recruiting
248
OptumCare Cancer Care at MountainView
Las Vegas, Nevada, United States, 89128
Actively Recruiting
249
Urology Specialists of Nevada - Northwest
Las Vegas, Nevada, United States, 89128
Actively Recruiting
250
Alliance for Childhood Diseases/Cure 4 the Kids Foundation
Las Vegas, Nevada, United States, 89135
Actively Recruiting
251
Comprehensive Cancer Centers of Nevada - Town Center
Las Vegas, Nevada, United States, 89144
Actively Recruiting
252
Comprehensive Cancer Centers of Nevada-Summerlin
Las Vegas, Nevada, United States, 89144
Actively Recruiting
253
Summerlin Hospital Medical Center
Las Vegas, Nevada, United States, 89144
Actively Recruiting
254
Las Vegas Cancer Center-Medical Center
Las Vegas, Nevada, United States, 89148-2405
Suspended
255
Comprehensive Cancer Centers of Nevada
Las Vegas, Nevada, United States, 89148
Actively Recruiting
256
GenesisCare USA - Fort Apache
Las Vegas, Nevada, United States, 89148
Actively Recruiting
257
OptumCare Cancer Care at Fort Apache
Las Vegas, Nevada, United States, 89148
Actively Recruiting
258
Comprehensive Cancer Centers of Nevada - Central Valley
Las Vegas, Nevada, United States, 89169
Actively Recruiting
259
University Cancer Center
Las Vegas, Nevada, United States, 89169
Actively Recruiting
260
Hope Cancer Care of Nevada-Pahrump
Pahrump, Nevada, United States, 89048
Actively Recruiting
261
Renown Regional Medical Center
Reno, Nevada, United States, 89502
Actively Recruiting
262
Saint Mary's Regional Medical Center
Reno, Nevada, United States, 89503
Actively Recruiting
263
Radiation Oncology Associates
Reno, Nevada, United States, 89509
Actively Recruiting
264
Dartmouth Hitchcock Medical Center/Dartmouth Cancer Center
Lebanon, New Hampshire, United States, 03756
Actively Recruiting
265
Hackensack University Medical Center
Hackensack, New Jersey, United States, 07601
Actively Recruiting
266
University of New Mexico Cancer Center
Albuquerque, New Mexico, United States, 87102
Actively Recruiting
267
Roswell Park Cancer Institute
Buffalo, New York, United States, 14263
Actively Recruiting
268
Northwell Health/Center for Advanced Medicine
Lake Success, New York, United States, 11042
Actively Recruiting
269
University of Rochester
Rochester, New York, United States, 14642
Actively Recruiting
270
Phelps Memorial Hospital Center
Sleepy Hollow, New York, United States, 10591
Actively Recruiting
271
Southeastern Medical Oncology Center-Clinton
Clinton, North Carolina, United States, 28328
Active, Not Recruiting
272
Southeastern Medical Oncology Center-Goldsboro
Goldsboro, North Carolina, United States, 27534
Active, Not Recruiting
273
Southeastern Medical Oncology Center-Jacksonville
Jacksonville, North Carolina, United States, 28546
Active, Not Recruiting
274
UH Seidman Cancer Center at UH Avon Health Center
Avon, Ohio, United States, 44011
Actively Recruiting
275
UHHS-Chagrin Highlands Medical Center
Beachwood, Ohio, United States, 44122
Actively Recruiting
276
Indu and Raj Soin Medical Center
Beavercreek, Ohio, United States, 45431
Actively Recruiting
277
Saint Elizabeth Boardman Hospital
Boardman, Ohio, United States, 44512
Actively Recruiting
278
Dayton Physicians LLC-Miami Valley South
Centerville, Ohio, United States, 45459
Actively Recruiting
279
Miami Valley Hospital South
Centerville, Ohio, United States, 45459
Suspended
280
University of Cincinnati Cancer Center-UC Medical Center
Cincinnati, Ohio, United States, 45219
Actively Recruiting
281
Oncology Hematology Care Inc-Kenwood
Cincinnati, Ohio, United States, 45236
Actively Recruiting
282
Case Western Reserve University
Cleveland, Ohio, United States, 44106
Actively Recruiting
283
Ohio State University Comprehensive Cancer Center
Columbus, Ohio, United States, 43210
Actively Recruiting
284
Miami Valley Hospital
Dayton, Ohio, United States, 45409
Suspended
285
Dayton Physician LLC-Miami Valley Hospital North
Dayton, Ohio, United States, 45415
Actively Recruiting
286
Miami Valley Hospital North
Dayton, Ohio, United States, 45415
Suspended
287
Armes Family Cancer Center
Findlay, Ohio, United States, 45840
Actively Recruiting
288
Blanchard Valley Hospital
Findlay, Ohio, United States, 45840
Actively Recruiting
289
Orion Cancer Care
Findlay, Ohio, United States, 45840
Actively Recruiting
290
Atrium Medical Center-Middletown Regional Hospital
Franklin, Ohio, United States, 45005-1066
Suspended
291
Dayton Physicians LLC-Atrium
Franklin, Ohio, United States, 45005
Actively Recruiting
292
Dayton Physicians LLC-Wayne
Greenville, Ohio, United States, 45331
Actively Recruiting
293
Wayne Hospital
Greenville, Ohio, United States, 45331
Actively Recruiting
294
Greater Dayton Cancer Center
Kettering, Ohio, United States, 45409
Actively Recruiting
295
Kettering Medical Center
Kettering, Ohio, United States, 45429
Actively Recruiting
296
UH Seidman Cancer Center at Lake Health Mentor Campus
Mentor, Ohio, United States, 44060
Actively Recruiting
297
Springfield Regional Cancer Center
Springfield, Ohio, United States, 45504
Suspended
298
Springfield Regional Medical Center
Springfield, Ohio, United States, 45505
Suspended
299
University of Toledo
Toledo, Ohio, United States, 43614
Suspended
300
Dayton Physicians LLC - Troy
Troy, Ohio, United States, 45373
Actively Recruiting
301
Upper Valley Medical Center
Troy, Ohio, United States, 45373
Suspended
302
Saint Joseph Warren Hospital
Warren, Ohio, United States, 44484
Actively Recruiting
303
University of Cincinnati Cancer Center-West Chester
West Chester, Ohio, United States, 45069
Actively Recruiting
304
Saint Elizabeth Youngstown Hospital
Youngstown, Ohio, United States, 44501
Actively Recruiting
305
University of Oklahoma Health Sciences Center
Oklahoma City, Oklahoma, United States, 73104
Suspended
306
Mercy Hospital Oklahoma City
Oklahoma City, Oklahoma, United States, 73120
Actively Recruiting
307
Kaiser Sunnyside Medical Center
Clackamas, Oregon, United States, 97015
Actively Recruiting
308
Rogue Valley Medical Center
Medford, Oregon, United States, 97504
Active, Not Recruiting
309
Kaiser Permanente Northwest
Portland, Oregon, United States, 97227
Actively Recruiting
310
Oregon Health and Science University
Portland, Oregon, United States, 97239
Actively Recruiting
311
UPMC Altoona
Altoona, Pennsylvania, United States, 16601
Actively Recruiting
312
UPMC-Heritage Valley Health System Beaver
Beaver, Pennsylvania, United States, 15009
Actively Recruiting
313
UPMC Hillman Cancer Center at Butler Health System
Butler, Pennsylvania, United States, 16001
Actively Recruiting
314
UPMC Hillman Cancer Center Erie
Erie, Pennsylvania, United States, 16505
Actively Recruiting
315
UPMC Cancer Center at UPMC Horizon
Farrell, Pennsylvania, United States, 16121
Actively Recruiting
316
UPMC Cancer Centers - Arnold Palmer Pavilion
Greensburg, Pennsylvania, United States, 15601
Actively Recruiting
317
IRMC Cancer Center
Indiana, Pennsylvania, United States, 15701
Actively Recruiting
318
UPMC-Johnstown/John P. Murtha Regional Cancer Center
Johnstown, Pennsylvania, United States, 15901
Actively Recruiting
319
UPMC Cancer Center at UPMC McKeesport
McKeesport, Pennsylvania, United States, 15132
Actively Recruiting
320
UPMC Hillman Cancer Center - Monroeville
Monroeville, Pennsylvania, United States, 15146
Actively Recruiting
321
UPMC Hillman Cancer Center - Part of Frick Hospital
Mount Pleasant, Pennsylvania, United States, 15666
Actively Recruiting
322
Arnold Palmer Cancer Center Medical Oncology Norwin
N. Huntingdon, Pennsylvania, United States, 15642
Actively Recruiting
323
UPMC Cancer Center-Natrona Heights
Natrona Heights, Pennsylvania, United States, 15065
Actively Recruiting
324
UPMC Hillman Cancer Center - New Castle
New Castle, Pennsylvania, United States, 16105
Actively Recruiting
325
UPMC-Saint Margaret
Pittsburgh, Pennsylvania, United States, 15215
Actively Recruiting
326
University of Pittsburgh Cancer Institute (UPCI)
Pittsburgh, Pennsylvania, United States, 15232
Actively Recruiting
327
UPMC-Shadyside Hospital
Pittsburgh, Pennsylvania, United States, 15232
Actively Recruiting
328
UPMC-Passavant Hospital
Pittsburgh, Pennsylvania, United States, 15237
Actively Recruiting
329
UPMC-Saint Clair Hospital Cancer Center
Pittsburgh, Pennsylvania, United States, 15243
Actively Recruiting
330
UPMC Cancer Center at UPMC Northwest
Seneca, Pennsylvania, United States, 16346
Actively Recruiting
331
UPMC Cancer Center-Uniontown
Uniontown, Pennsylvania, United States, 15401
Actively Recruiting
332
UPMC Cancer Center-Washington
Washington, Pennsylvania, United States, 15301
Actively Recruiting
333
UPMC West Mifflin-Cancer Center Jefferson
West Mifflin, Pennsylvania, United States, 15122
Actively Recruiting
334
Prisma Health Cancer Institute - Spartanburg
Boiling Springs, South Carolina, United States, 29316
Active, Not Recruiting
335
Medical University of South Carolina
Charleston, South Carolina, United States, 29425
Actively Recruiting
336
Prisma Health Cancer Institute - Easley
Easley, South Carolina, United States, 29640
Active, Not Recruiting
337
Prisma Health Cancer Institute - Butternut
Greenville, South Carolina, United States, 29605
Active, Not Recruiting
338
Prisma Health Cancer Institute - Faris
Greenville, South Carolina, United States, 29605
Active, Not Recruiting
339
Prisma Health Greenville Memorial Hospital
Greenville, South Carolina, United States, 29605
Active, Not Recruiting
340
Prisma Health Cancer Institute - Eastside
Greenville, South Carolina, United States, 29615
Active, Not Recruiting
341
Prisma Health Cancer Institute - Greer
Greer, South Carolina, United States, 29650
Active, Not Recruiting
342
Prisma Health Cancer Institute - Seneca
Seneca, South Carolina, United States, 29672
Active, Not Recruiting
343
UT Southwestern Simmons Cancer Center - RedBird
Dallas, Texas, United States, 75237
Actively Recruiting
344
UT Southwestern/Simmons Cancer Center-Dallas
Dallas, Texas, United States, 75390
Actively Recruiting
345
UT Southwestern/Simmons Cancer Center-Fort Worth
Fort Worth, Texas, United States, 76104
Actively Recruiting
346
Baylor College of Medicine/Dan L Duncan Comprehensive Cancer Center
Houston, Texas, United States, 77030
Actively Recruiting
347
Ben Taub General Hospital
Houston, Texas, United States, 77030
Actively Recruiting
348
UT Southwestern Clinical Center at Richardson/Plano
Richardson, Texas, United States, 75080
Actively Recruiting
349
University of Texas Health Science Center at San Antonio
San Antonio, Texas, United States, 78229
Actively Recruiting
350
University of Utah Sugarhouse Health Center
Salt Lake City, Utah, United States, 84106
Actively Recruiting
351
Huntsman Cancer Institute/University of Utah
Salt Lake City, Utah, United States, 84112
Actively Recruiting
352
George E Wahlen Department of Veterans Affairs Medical Center
Salt Lake City, Utah, United States, 84148
Actively Recruiting
353
Norris Cotton Cancer Center-North
Saint Johnsbury, Vermont, United States, 05819
Actively Recruiting
354
Overlake Medical Center
Bellevue, Washington, United States, 98004
Suspended
355
Valley Medical Center
Renton, Washington, United States, 98055
Actively Recruiting
356
North Star Lodge Cancer Center at Yakima Valley Memorial Hospital
Yakima, Washington, United States, 98902
Actively Recruiting
357
Aurora Cancer Care-Southern Lakes VLCC
Burlington, Wisconsin, United States, 53105
Actively Recruiting
358
Marshfield Clinic-Chippewa Center
Chippewa Falls, Wisconsin, United States, 54729
Actively Recruiting
359
Marshfield Medical Center-EC Cancer Center
Eau Claire, Wisconsin, United States, 54701
Actively Recruiting
360
Aurora Health Care Germantown Health Center
Germantown, Wisconsin, United States, 53022
Actively Recruiting
361
Aurora Cancer Care-Grafton
Grafton, Wisconsin, United States, 53024
Actively Recruiting
362
Aurora BayCare Medical Center
Green Bay, Wisconsin, United States, 54311
Actively Recruiting
363
Aurora Cancer Care-Kenosha South
Kenosha, Wisconsin, United States, 53142
Actively Recruiting
364
Marshfield Clinic - Ladysmith Center
Ladysmith, Wisconsin, United States, 54848
Actively Recruiting
365
Aurora Bay Area Medical Group-Marinette
Marinette, Wisconsin, United States, 54143
Actively Recruiting
366
Marshfield Medical Center-Marshfield
Marshfield, Wisconsin, United States, 54449
Actively Recruiting
367
Froedtert Menomonee Falls Hospital
Menomonee Falls, Wisconsin, United States, 53051
Actively Recruiting
368
Aurora Cancer Care-Milwaukee
Milwaukee, Wisconsin, United States, 53209
Actively Recruiting
369
Aurora Saint Luke's Medical Center
Milwaukee, Wisconsin, United States, 53215
Actively Recruiting
370
Medical College of Wisconsin
Milwaukee, Wisconsin, United States, 53226
Actively Recruiting
371
Aurora Sinai Medical Center
Milwaukee, Wisconsin, United States, 53233
Actively Recruiting
372
Marshfield Clinic-Minocqua Center
Minocqua, Wisconsin, United States, 54548
Actively Recruiting
373
Cancer Center of Western Wisconsin
New Richmond, Wisconsin, United States, 54017
Actively Recruiting
374
Drexel Town Square Health Center
Oak Creek, Wisconsin, United States, 53154
Actively Recruiting
375
Vince Lombardi Cancer Clinic - Oshkosh
Oshkosh, Wisconsin, United States, 54904
Actively Recruiting
376
Aurora Cancer Care-Racine
Racine, Wisconsin, United States, 53406
Actively Recruiting
377
Marshfield Medical Center-Rice Lake
Rice Lake, Wisconsin, United States, 54868
Actively Recruiting
378
Vince Lombardi Cancer Clinic-Sheboygan
Sheboygan, Wisconsin, United States, 53081
Actively Recruiting
379
Marshfield Medical Center-River Region at Stevens Point
Stevens Point, Wisconsin, United States, 54482
Actively Recruiting
380
Aurora Medical Center in Summit
Summit, Wisconsin, United States, 53066
Actively Recruiting
381
Vince Lombardi Cancer Clinic-Two Rivers
Two Rivers, Wisconsin, United States, 54241
Actively Recruiting
382
Marshfield Clinic-Wausau Center
Wausau, Wisconsin, United States, 54401
Actively Recruiting
383
Aurora Cancer Care-Milwaukee West
Wauwatosa, Wisconsin, United States, 53226
Actively Recruiting
384
Aurora West Allis Medical Center
West Allis, Wisconsin, United States, 53227
Actively Recruiting
385
Froedtert West Bend Hospital/Kraemer Cancer Center
West Bend, Wisconsin, United States, 53095
Actively Recruiting
386
Marshfield Medical Center - Weston
Weston, Wisconsin, United States, 54476
Actively Recruiting
387
Marshfield Clinic - Wisconsin Rapids Center
Wisconsin Rapids, Wisconsin, United States, 54494
Actively Recruiting
Research Team
M
Megan Keim, MS
CONTACT
D
Dana Sparks, MAT
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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