Study Comparing CT and MRI VI-RADS for Local Staging of New Bladder Cancer

What this Trial Is About

Researchers are evaluating the accuracy of computed tomography CT versus multiparametric magnetic resonance imaging MRI using the Vesical Imaging-Reporting and Data System VI-RADS for local staging of newly diagnosed bladder cancer. This study aims to improve the distinction between non-muscle-invasive and muscle-invasive bladder cancer, which is critical for guiding treatment decisions. Previous studies suggest MRI may have better diagnostic performance, but prospective comparisons in the same patients are limited. All participants receive both contrast-enhanced CT and multiparametric MRI scans before undergoing transurethral resection of the bladder tumor TURBT or cystectomy. Two radiologists independently review the imaging results without knowing each others assessments or patient details. Imaging findings are then compared to biopsy or surgery results to determine the accuracy of each method. During the study, participants undergo cystoscopy and the two imaging tests prior to surgery. Researchers measure how well each imaging technique detects muscle-invasive bladder cancer and correctly classifies tumor stage over up to 12 months. They also assess agreement between radiologists and analyze tumor characteristics. The study helps understand which imaging method better supports treatment planning for bladder cancer.

Comparison of CT and MR (VI-RADS) Imaging for Local Bladder Cancer Staging