Actively Recruiting

Phase 4
Age: 12Years - 17Years
All Genders
ID07192367

Comparison of Virtual Reality Exposure Therapy and Sertraline Treatment for Social Anxiety Disorder in Adolescents and Young Adults

Led by Emine Kanmaz · Updated on 2025-09-25

56

Participants Needed

1

Research Sites

17 weeks

Total Duration

On this page

Sponsors

E

Emine Kanmaz

Lead Sponsor

K

Kocaeli University

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to compare two treatment methods for adolescents and young adults aged 12 to 17 years with social anxiety disorder (SAD). It evaluates virtual reality exposure therapy against sertraline, a commonly prescribed medication, to see which approach better reduces anxiety symptoms and improves daily functioning. The study also assesses how acceptable and safe these treatments are for participants. Conducted at Kocaeli University, Department of Child and Adolescent Psychiatry, the study includes 56 participants. Participants will be assigned to one of two groups based on their treatment preference. One group will undergo virtual reality exposure therapy using a VR headset to simulate social situations like public speaking and group interactions in a controlled environment. The other group will receive sertraline medication, with dosage guided by clinical standards and physician judgment. The study includes treatment sessions and medication follow-ups over a 12-week period. During the study, participants will be assessed at the start, week 6, and week 12 using standardized scales to measure changes in social anxiety symptoms, social phobia symptoms, and overall anxiety. Researchers will monitor treatment acceptability and safety throughout the trial. The total involvement spans 12 weeks, with ongoing clinical observations and symptom evaluations to understand treatment effects and participant experiences.

CONDITIONS

Brief Title

Comparison of the Effectiveness Level of Virtual Reality Exposure Therapy With Sertraline Treatment in Social Anxiety Disorder

Who Can Participate

Age: 12Years - 17Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Be between 12 and 17 years of age
  • Have a diagnosis of social anxiety disorder (SAD)
  • Have normal intelligence based on clinical observation
  • Applied to Kocaeli University Child and Adolescent Psychiatry Outpatient Clinic
  • For the research arm: Have refused medication recommended for SAD
  • For the research arm: Not currently receiving medical treatment for SAD
  • For the control arm: Accept sertraline treatment for SAD
  • Have received written consent to participate from the participant and/or authorized first-degree relatives
  • Volunteered to participate in the study through an invitation poster presentation
Not Eligible

You will not qualify if you...

  • History of substance use disorder
  • Diagnosis of schizophrenia or bipolar disorder
  • Diagnosis of autism spectrum disorder
  • Cognitive disability
  • Neurological disorder (research arm only)
  • Balance disorder (research arm only)
  • Received SSRI treatment for SAD in the last 6 months

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Outpatient Treatment

Duration - 12 weeks

Participants receive either Virtual Reality Exposure Therapy sessions or Sertraline treatment to reduce social anxiety symptoms.

Weekly visits for up to 12 weeks

Follow-up Assessments

Duration - 12 weeks

Participants are assessed for changes in social anxiety, social phobia, and anxiety symptoms at weeks 6 and 12.

2 visits (in-person) at Week 6 and Week 12

Trial Site Locations

Total: 1 location

1

Kocaeli University Hospital - Department of Child and Adolescent Psychiatry

Kocaeli, Turkey (Türkiye), 41000

Actively Recruiting

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Research Team

E

Emine Kayış, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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