Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
ID07398352

Comparison of Interscalene Block Alone Versus Combined Interscalene and Superficial Cervical Blocks on Brain Oxygenation and Carotid Artery Diameter in Shoulder Surgery

Led by Sanliurfa Mehmet Akif Inan Education and Research Hospital · Updated on 2026-03-24

70

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating how two types of regional anesthesia affect brain oxygen levels and carotid artery size during shoulder surgery. The study compares the use of an interscalene block alone versus a combination of interscalene block and superficial cervical plexus block. These nerve blocks are often used to manage pain in shoulder surgeries and the study aims to understand their effects on brain oxygenation, blood flow, and postoperative pain. Participants will receive one of two anesthesia approaches under ultrasound guidance after sedation with midazolam. The first group will get an interscalene brachial plexus block alone, and the second group will receive both interscalene and superficial cervical plexus blocks. Oxygen levels in both brain hemispheres and carotid artery diameter will be measured multiple times before, during, and after surgery using near-infrared spectroscopy and ultrasonography. During the study, patients will be monitored closely with repeated measurements of cerebral oxygen saturation and carotid artery size at specific time points including before block, during surgery in the beach chair position, and postoperatively while supine. Sensory block quality and pain levels will be assessed, with recording of the time to first postoperative pain and need for analgesics. The study also tracks opioid use up to 24 hours after surgery to evaluate pain management. Participants are involved from sedation through surgery and recovery with careful monitoring of their brain and vascular responses.

CONDITIONS

Brief Title

Comparison Of The Effects Of Regional Anesthesia On Brain And Carotid Artery Oxygenation In Shoulder Surgery

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients aged 18 to 65 years
  • American Society of Anesthesiologists (ASA) physical status I or II
Not Eligible

You will not qualify if you...

  • Age under 18 years or over 65 years
  • History of carotid endarterectomy
  • History of cerebrovascular accident (stroke)
  • Body Mass Index (BMI) greater than 35 kg/m²
  • Inability to cooperate or follow study procedures
  • Liver or kidney failure
  • Pregnancy or breastfeeding
  • ASA physical status III to V
  • Contraindication to regional anesthesia

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Treatment

Duration - Duration of shoulder surgery and immediate postoperative period

Participants receive either an interscalene brachial plexus block alone or a combination of interscalene and superficial cervical plexus blocks under ultrasound guidance with sedation. Brain oxygenation and carotid artery diameter are measured before, during, and after the block and surgery to assess the effects of the anesthesia techniques. Sensory block quality is evaluated, and participants are monitored for pain and analgesic requirements postoperatively.

1 baseline visit and multiple intraoperative and postoperative assessments during surgery and up to 5 minutes after surgery

Trial Site Locations

Total: 1 location

1

Sanliurfa Mehmet Akif Inan Education and Research Hospital

Sanliurfa, Turkey (Türkiye)

Actively Recruiting

Loading map...

Research Team

R

Ramazan ASLANPARÇASI, MD

T

Tuğba BINGOL TANRIVERDI, MD

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

Similar Trials

Evaluation of Cerebral Oxygenation During Orthopedic Surgeri...

Cerebral Perfusion

Actively Recruiting

2 locations

Interscalene Block Versus Anterior Suprascapular Block for P...

Interscalene Block

Actively Recruiting

1 location

The Effects of the Female Sex Hormones and Hormonal Contrace...

Cerebral Perfusion

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here

Published Research Related To This Trial

Efficacy of Suprascapular Versus Interscalene Block for Post-Operative Pain Management in Shoulder Surgeries: A Narrative Review.

Shahab Ahmadzadeh, Blake P Naccari, Lane S Amedio...

https://pubmed.ncbi.nlm.nih.gov/41457137

Could Interscalene Block Possibly be Protective Against Cerebral Ischemia During Shoulder Surgery in a Beach Chair Position?

Sami Kaan Coşarcan, Yavuz Gurkan, Alper Tunga Doğan...

https://pubmed.ncbi.nlm.nih.gov/34476141