Actively Recruiting
Comparison of Genotype-Based Dietary Counseling Versus Standard Dietary Counseling on Weight Loss and Fat Mass Reduction
Led by Metropolitan College · Updated on 2026-01-28
88
Participants Needed
1
Research Sites
8 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying the effects of dietary counseling tailored by genetic information compared to standard dietary guidance based on general recommendations. The aim is to evaluate which approach better supports weight loss and reduction of body fat in adults with overweight or obesity over a 12-month period. This trial involves adults aged 18 to 65 years with a body mass index of 25 kg/m² or higher. Participants are randomly assigned to one of two groups. One group receives dietary counseling personalized according to their genetic profile, combined with standard nutritional principles. The other group receives general dietary counseling based on conventional guidelines without genetic information. Both types of counseling are delivered by qualified nutrition professionals throughout the intervention period. During the study, researchers will assess changes in fat mass percentage, body weight, and lipid profiles from the start to the end of the 12-month intervention. Participants will engage in dietary counseling sessions and study assessments as scheduled. The study also monitors participants’ adherence to the counseling and evaluates safety and health measures throughout the trial duration.
CONDITIONS
Brief Title
Comparison of Genotype-Based Dietary Counseling Versus Standard Dietary Counseling on Weight Loss and Fat Mass Reduction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Adults aged 60 years
- Body mass index (BMI) 60 25 kg/m�b2
- Able to read and understand Greek and provide informed consent
- Willing and able to participate in dietary counseling and study assessments for the study duration
You will not qualify if you...
- Current use of medications for weight loss such as GLP-1 receptor agonists or appetite suppressants
- Participation in any structured weight-loss program in the past 3 months
- Use of medications affecting body weight or composition like corticosteroids or antipsychotics
- Pregnancy or breastfeeding
- Medical conditions affecting weight, metabolism, or nutrition such as untreated thyroid disease or severe gastrointestinal disorders
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 12 months
Participants receive dietary counseling either tailored to their genetic profile or based on general dietary guidelines. Counseling is provided by qualified nutrition professionals to support weight loss and fat mass reduction.
Regular counseling sessions over 12 months
Trial Site Locations
Total: 1 location
1
Dietetics Department, School of Health Sciences, Metropolitan College
Marousi, Greece, 151 25
Actively Recruiting
Research Team
A
Angeliki Kapellou, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
SINGLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
OTHER
Number of Arms
2
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