Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
NCT07036445

Comparison of Interlaminar CT Guided Epidural Platelet Rich Plasma Versus Steroid Injection in Patients With Lumbar Radicular Pain

Led by Clinique du Sport, Bordeaux Mérignac · Updated on 2025-09-18

200

Participants Needed

1

Research Sites

172 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The treatment of persistent lumbar radicular pain (LRP) using CT-guided epidural steroid injection (ESI) is widely used and associated with rare but serious complications. Platelet-rich plasma (PRP), which has recently been shown to promote healing and the anti-inflammatory process by delivering growth factors and cytokines, could be an alternative and potentially safer option. A previous study showed that PRP was as effective as ESI in treating this condition, without major complications. This study aims to compare these two treatments over the long term (2 years).

CONDITIONS

Official Title

Comparison of Interlaminar CT Guided Epidural Platelet Rich Plasma Versus Steroid Injection in Patients With Lumbar Radicular Pain

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of unilateral resistant lumbar radicular pain associated with a herniated disc on MRI images
  • Resistance to treatment after 6 weeks of appropriate medical care
  • Adults aged 18 years and older
Not Eligible

You will not qualify if you...

  • Presence of infections
  • Previous percutaneous corticosteroid injections
  • Current systemic corticosteroid treatment
  • Immune deficiencies
  • Allergy to contrast medium used
  • Pregnancy or breastfeeding
  • History of allergies to anesthetics or corticosteroids
  • Anticoagulant treatment or blood disorders, including antiplatelet therapy
  • Use of NSAIDs within two weeks prior to the procedure

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Clinique du Sport

Mérignac, France, 33700

Actively Recruiting

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How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

RANDOMIZED

Model

PARALLEL

Primary Purpose

TREATMENT

Number of Arms

2

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Comparison of Interlaminar CT Guided Epidural Platelet Rich Plasma Versus Steroid Injection in Patients With Lumbar Radicular Pain | DecenTrialz