Actively Recruiting
Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer
Led by Blokhin's Russian Cancer Research Center · Updated on 2025-08-12
30
Participants Needed
1
Research Sites
178 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
GENCONCOR-1 study is translational research aimed to investigate the concordance of the molecular genetic profile of the primary tumor and brain metastases (BM) of colorectal cancer (CRC). The study was conducted by post hoc analysis of pairs of samples of histological material with determination of the mutational status of genes KRAS, NRAS, BRAF, HER2 and MSI.
CONDITIONS
Official Title
Comparison of Molecular-Genetic Concordance of the Primary Tumor and Brain Metastases of Colorectal Cancer
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Men and women over 18 years of age
- Histologically confirmed cancer of the colon or rectum
- Histologically confirmed metastatic lesion of the brain
- Neurosurgical resection for brain metastases of colorectal cancer
- Availability of paired tumor samples from both primary tumor and brain metastases
You will not qualify if you...
- Missing one sample from a pair of tumor samples
- Low quality or lack of tumor material for molecular genetic research
AI-Screening
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Trial Site Locations
Total: 1 location
1
Blokhin's Russian Cancer Research Center
Moscow, Moscow, Russia, 115478
Actively Recruiting
Research Team
D
David Halafyan, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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