Actively Recruiting
A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain
Led by Memorial Sloan Kettering Cancer Center · Updated on 2026-02-11
62
Participants Needed
7
Research Sites
208 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The purpose of the study is to see if stereotactic radiosurgery/SRS is an effective treatment for people with a new diagnosis of brain metastases from small cell lung cancer/SCLC.
CONDITIONS
Official Title
A Study of Stereotactic Radiosurgery (SRS) for People With Lung Cancer That Has Spread to the Brain
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Histologic diagnosis of small cell lung cancer
- Radiographic diagnosis of up to 20 brain metastases on contrast-enhanced MRI
- Age 18 and above
- Performance status KPS 60-100 or ECOG 0-2
- Female patients must be of non-reproductive potential or have a negative serum pregnancy test at enrollment
- Ability of the patient or legally authorized representative to provide informed consent
You will not qualify if you...
- Unable to undergo contrast-enhanced MRI of the brain
- Leptomeningeal disease confirmed by lumbar puncture, brain MRI, or spine MRI
- Pregnant or lactating women
- Prior brain-directed radiotherapy
- Uncontrolled systemic disease without reasonable systemic therapy options likely to cause death within 3 months before enrollment
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 7 locations
1
Memorial Sloan Kettering at Basking Ridge
Basking Ridge, New Jersey, United States, 07920
Actively Recruiting
2
Memorial Sloan Kettering Monmouth
Middletown, New Jersey, United States, 07748
Actively Recruiting
3
Memorial Sloan Kettering Bergen
Montvale, New Jersey, United States, 07645
Actively Recruiting
4
Memorial Sloan Kettering Suffolk - Commack
Commack, New York, United States, 11725
Actively Recruiting
5
Memorial Sloan Kettering Westchester
Harrison, New York, United States, 10604
Actively Recruiting
6
Memorial Sloan Kettering Cancer Center (All Protocol Activities)
New York, New York, United States, 10065
Actively Recruiting
7
Memorial Sloan Kettering Nassau
Rockville Centre, New York, United States, 11553
Actively Recruiting
Research Team
L
Luke Pike, MD
CONTACT
B
Brandon Imber, MD
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
TREATMENT
Number of Arms
1
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