Actively Recruiting

Age: 18Years +
All Genders
ID06265649

Acute Left Colon Diverticulitis Non-Operative Management Comparison Between Surgical and Medical Wards Retrospective Study

Led by Ospedali Riuniti Trieste · Updated on 2025-04-04

175

Participants Needed

1

Research Sites

4 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are investigating acute left colon diverticulitis (ALCD), a common gastrointestinal disorder that mainly affects the left side of the colon. The study focuses on patients with ALCD who are treated without surgery, comparing outcomes between those admitted to surgical wards and those admitted to non-surgical medical wards. This study aims to understand differences in clinical results, length of hospital stay, and follow-up care between these two hospital settings. Participants receive non-operative management (NOM) for ALCD, which includes monitoring lab tests, fluid therapy, antibiotic treatment, abscess drainage if larger than 4 cm, and gradually restoring a regular diet. The study groups are divided based on the hospital ward patients are admitted to: either a surgical ward or a medical ward, with admission decided by bed availability. This observational study uses data collected retrospectively and compares patients matched by disease severity to reduce bias. During the study, researchers will review patient data including age, sex, body mass index, previous episodes, inflammatory markers, and treatment details. They will monitor hospital stay length and follow patients for two years to track recurrences and follow-up visits. Outcomes include hospitalization duration, clinical recovery such as symptom resolution and diet restoration, and long-term recurrence rates. The study is scheduled to complete in January 2026.

CONDITIONS

Brief Title

Comparison of NOM for ACLD Between Medical and Surgical Ward

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed with acute left colon diverticulitis confirmed by contrast-enhanced CT scan at admission
  • Patients undergoing non-operative management (NOM) for ALCD
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Immediate indication for surgery (Hinchey III or IV ALCD)
  • Septic patients with Hinchey II ALCD requiring urgent surgery

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

1
2
3
+1

Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person)

Monitoring

Duration - Up to 1 month after admission

Participants diagnosed with acute left colon diverticulitis and undergoing non-operative management (NOM) are observed during their hospital stay in either surgical or medical wards. This includes lab test monitoring, fluid therapy, antibiotic therapy, abscess drainage if needed, and restoring a regular diet.

Hospitalization with daily monitoring visits

Long-term Monitoring

Duration - 2 years after discharge

Participants are followed up for two years after discharge to assess clinical outcomes, including recurrences and follow-up visits.

Periodic follow-up visits as per clinical records

Trial Site Locations

Total: 1 location

1

Manuela Mastronardi

Trieste, TS, Italy, 34149

Actively Recruiting

Loading map...

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

Similar Trials

A Randomised Controlled Trial to Compare Efficacy and Tolera...

Colon Disease

Actively Recruiting

1 location

Anastomotic Bleeding in Primary Double-stapled Colorectal An...

Colorectal Cancer

Actively Recruiting

1 location

Risk Factors for Anastomotic Leakage After Colorectal Surger...

Anastomotic Leak

Actively Recruiting

1 location

Frequently Asked Questions

Have more questions? Get in touch with our team for quick support

Not the Right Trial for You?

Explore thousands of other clinical trials that might be a better match.
Sign up to get personalized trial recommendations delivered to your inbox.

Already have an account? Log in here