Actively Recruiting

Age: 18Years - 74Years
All Genders
Healthy Volunteers
NCT05278520

Complex Molecular Etiology and Cellular Landscape of Hip Osteoarthritis

Led by University of Turku · Updated on 2025-08-24

110

Participants Needed

4

Research Sites

307 weeks

Total Duration

On this page

Sponsors

U

University of Turku

Lead Sponsor

T

Turku University Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The purpose of this study is to cast light on the highly complex etiology and cellular landscape of hip osteoarthritis by utilising single-cell and spatial omics.

CONDITIONS

Official Title

Complex Molecular Etiology and Cellular Landscape of Hip Osteoarthritis

Who Can Participate

Age: 18Years - 74Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Adult patients with osteoarthritis in the hip joint undergoing elective total hip arthroplasty
  • Non-arthritis adult patients undergoing trauma-based emergency total hip arthroplasty as controls
  • Adult patients with rheumatoid arthritis in the hip joint undergoing elective total hip arthroplasty (Rheumatoid sub-study)
Not Eligible

You will not qualify if you...

  • Body mass index (BMI) must be below 35
  • Age under 18 or over 74 years
  • Osteoarthritis patients may not have diabetes, rheumatoid arthritis, or metabolic syndrome
  • Rheumatoid sub-study excludes the same criteria except for rheumatoid arthritis

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 4 locations

1

PET-centre, University of Turku

Turku, Southwest Finland, Finland

Active, Not Recruiting

2

Turku Bioscience, University of Turku

Turku, Southwest Finland, Finland

Active, Not Recruiting

3

Turku University Hospital

Turku, Southwest Finland, Finland

Actively Recruiting

4

Helsinki University Hospital

Espoo, Uusimaa, Finland

Actively Recruiting

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Research Team

L

Lea Mikkola, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

3

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