Adhesive Capsulitis (Frozen Shoulder)

Researchers are evaluating the impact of a three-dimensional mobilization technique called 3-Dimensional Shoulder Complex Pain Alignment (3-D SPA) on improving shoulder mobility in patients with frozen shoulder. This condition involves inflammation, stiffness, and pain that limit movement and daily activities, especially in women aged 35 to 65 years. The study aims to reduce pain, muscle tightness, and improve range of motion by addressing restrictions in all three planes of shoulder movement. The trial compares two groups of 36 participants each. One group receives the 3-D SPA mobilization combined with conventional therapy and a home exercise plan, while the other group receives Kaltenborn shoulder mobilization with conventional therapy and home exercises. Both groups undergo treatment sessions three times per week for three weeks, including 5 minutes of mobilization and 30 minutes of exercises per session. Ultrasound therapy is also applied continuously during each session. Participants will be assessed before and after the three-week treatment period using various measures such as the Shoulder Pain and Disability Index, range of motion in different shoulder movements, Visual Analogue Scale for pain, WHO Quality of Life questionnaire, and Apley's Scratch Test. Data will be analyzed to determine the effectiveness of the 3-D SPA technique in improving pain, disability, and shoulder function. The study includes safety monitoring and follow-up evaluations during and after treatment.

Researchers are studying a condition called adhesive capsulitis, also known as frozen shoulder. The study aims to evaluate the safety and effects of bevacizumab, a drug injected directly into the shoulder joint, and to determine the highest dose that can be given without causing serious side effects. This phase II trial is led by Macquarie University and will include up to 28 adults diagnosed with frozen shoulder. Participants will receive a single injection of bevacizumab in one of four doses: 50mg, 100mg, 150mg, or 200mg. The trial uses a dose-escalation design, starting with low doses and increasing only if safety allows. After the injection, participants will be monitored closely for dose-limiting toxicities before moving to higher doses or stopping if side effects occur. The highest dose planned is 200mg, with up to 10 participants in this group unless safety concerns arise. Over the next year, participants will visit the study site six times for safety checks, pain questionnaires, and movement tests led by a physiotherapist. Researchers will assess the safety of bevacizumab over 52 weeks and identify the maximum tolerated dose within one week after injection. They will also track how well the treatment works to reduce symptoms of frozen shoulder during this period.

Researchers are investigating the role of acupuncture in managing pain and improving outcomes after total knee replacement surgery (TKA) for patients with primary osteoarthritis. This study aims to assess whether acupuncture can help control acute pain, prevent chronic pain, improve joint function, and increase patient satisfaction. The research also examines how acupuncture influences inflammation by measuring specific biomarkers, which may relate to recovery and long-term joint stiffness. Participants will receive standard anesthesiology care including sedation, regional nerve blocks, and pain medications. They will be randomly assigned to either a standard treatment group or an acupuncture group, which receives additional acupuncture and auriculotherapy sessions before and after surgery. The acupuncture treatment targets specific body and ear points over multiple sessions during the first three days post-surgery. Throughout the study, participants will be monitored regularly for pain levels, medication use, vital signs, joint mobility, and rehabilitation progress. Blood samples will be taken before surgery and at set intervals afterward to measure inflammation markers. Patient-reported outcomes and satisfaction will be collected up to one year post-surgery. Evaluations will be done in person or by phone if necessary, with the entire follow-up extending through one year after the operation.

Researchers are studying patients with subacute stroke to evaluate the additional effects of kinesio taping combined with conventional physical therapy on upper limb function, range of motion, and spasticity. This randomized control trial aims to determine whether adding kinesio taping provides significant improvements compared to physical therapy alone. The study is conducted in rehabilitation settings and includes adults aged 40 to 65 years with a history of diagnosed stroke and moderate spasticity. Participants are divided into two groups. The experimental group receives kinesio taping three times per week along with physical therapy exercises including passive and active range of motion (ROM), PNF stretching, D1 flexion and extension movements, and resistance training with a medium resistance band from weeks 3 to 6. The control group receives the same physical therapy regimen but without kinesio taping. Treatments last 30 minutes on alternate days over six weeks. During the study, participants' upper limb spasticity and function are assessed at baseline, week 3, and week 6 using the Modified Ashworth Scale and the Wolf Motor Function Test. Range of motion is measured with a goniometer for shoulder, elbow, and wrist joints. Data collection includes demographic information and questionnaires. The study monitors outcomes throughout the six-week treatment period to analyze differences between groups.

This research aims to evaluate the additional effects of the Niel-Asher technique combined with sleeper stretch and conventional physical therapy on reducing pain, improving shoulder ranges of motion, and enhancing functional ability in patients with Adhesive Capsulitis, also known as frozen shoulder. Adhesive capsulitis is a painful condition marked by stiffness and reduced movement in the shoulder joint, often caused by fibrosis and contracture of the joint capsule. It is more common in females aged 40 to 60 and leads to significant limitations in shoulder rotation and other movements. The study compares two treatment approaches: one group receives the Niel-Asher technique along with sleeper stretch and conventional therapy, while the other group receives only sleeper stretch and conventional therapy. The Niel-Asher technique involves deep stroking massage and compression of trigger points on major shoulder muscles, applied three times a week for four weeks. Sleeper stretch is applied passively by the investigator to improve shoulder flexibility, also three times a week. Conventional therapy includes joint glides, active and assisted range of motion exercises, isometric exercises, Codman's and pulley exercises, and ischemic pressure to release trigger points. Participants will be involved in treatment sessions over four weeks, with assessments at the end of this period. Researchers will measure pain levels using the Visual Analogue Scale (VAS), shoulder function and disability with the Shoulder Pain and Disability Index (SPADI), and shoulder range of motion using a goniometer. These measures will help evaluate how the treatments affect pain, movement, and daily function. The trial is randomized and single-blinded, with follow-up planned to monitor progress and treatment effects up to four weeks.

Adhesive capsulitis, also known as frozen shoulder, is a painful condition that limits shoulder movement and causes significant functional difficulties. Traditional treatments focus mainly on the shoulder joint itself, often overlooking the role of nearby areas like the thoracic spine. Recent findings suggest that improving thoracic spine mobility may help shoulder function, but this approach has not been widely tested for adhesive capsulitis. This study aims to assess whether adding thoracic spine mobilization to standard shoulder joint therapy can better relieve pain, improve range of motion, and enhance functional ability. The trial is a randomized controlled study where participants diagnosed with adhesive capsulitis will be assigned to one of two groups. One group will receive both thoracic spine mobilization and glenohumeral joint mobilization, while the other group will receive only glenohumeral joint mobilization. Thoracic spine mobilization involves specific oscillatory movements aimed at improving spinal extension and rotation, while shoulder mobilization includes targeted oscillations to restore joint movement. Treatments will be delivered over a set period, with techniques clearly defined for each group to compare their effects. Participants will be evaluated before and after treatment using the Numeric Pain Rating Scale to measure pain, the Shoulder Pain and Disability Index to assess functional limitations, and a goniometer to record shoulder range of motion. Data will be analyzed to determine if the combined treatment improves outcomes more than shoulder mobilization alone. The study will run for one year and aims to provide evidence supporting more comprehensive rehabilitation strategies for adhesive capsulitis.

Researchers are evaluating treatments for adhesive capsulitis, also known as frozen shoulder, in adults aged 18 and older. This study compares two approaches: one involving physical therapy combined with steroid injections, and the other using steroid injections followed by watchful waiting. The goal is to determine if adding physical therapy significantly improves patient outcomes and if the extra cost is justified. Adhesive capsulitis causes pain and limited shoulder movement due to inflammation and scar tissue formation. Participants are randomly assigned to one of two groups. The first group receives physical therapy alongside steroid injections during the inflammatory phase, specifically 40 mg of depot methylprednisolone with lidocaine. The second group receives only steroid injections during the inflammatory phase, followed by regular observation without physical therapy. Both interventions follow standard care practices, with no experimental treatments involved. During the study, participants will have scheduled follow-up visits over a period extending up to one year. Researchers will assess functional outcomes using standardized questionnaires such as the American Shoulder and Elbow Surgeons Standardized Questionnaire, the Disabilities of the Arm, Shoulder, and Hand (DASH) score, and the Constant Shoulder Score. The study also evaluates patient satisfaction, physical exam findings, and return to athletics. The aim is to monitor recovery, range of motion, and the financial impact of treatments over time.

This research aims to analyze patients who come to the emergency department with anterior shoulder dislocation. The study focuses on documenting patient demographics, injury causes, orthopedic classifications, treatment methods, pain scores before and after procedures, and the time spent in the emergency department. The goal is to see if any current treatment approach leads to better emergency outcomes for these patients. Patients will be observed as they receive one of four types of analgesic treatments chosen by their doctors: ketamine, interscalene nerve block, suprascapular nerve block, or intraarticular lidocaine injection. The study will not change how treatments are given but will compare these groups based on pain management, time needed for shoulder reduction, patient comfort, and hospital stay length. Participants will be followed during their emergency department visit to collect data on treatments, pain levels, and outcomes such as discharge or admission to a ward. Researchers will review these details within 24 hours, focusing on the shoulder reduction process. The study includes monitoring patient outcomes related to their treatment and emergency stay duration without interfering in medical care.

This clinical trial studies two groups in rural settings: healthcare personnel and patients with shoulder pain lasting more than six months. The research aims to assess how usable and satisfying the TRAK tele-rehabilitation tool is for both groups. The study seeks to compare this digital approach with conventional rehabilitation exercises typically done at home. Patients with shoulder pain will be randomly assigned to either use the TRAK platform for eight weeks or follow a paper-based exercise protocol based on usual care. Healthcare professionals will use the TRAK tool throughout the study to prescribe exercises, monitor progress, and communicate with patients. Exercise frequency is personalized by healthcare providers, ranging from 3 to 7 days per week. Participants will complete quality of life and shoulder function assessments at the start and end of the study. Researchers will also gather feedback on the telemedicine usability and satisfaction after eight weeks. The study includes baseline health assessments, questionnaires, and a final face-to-face visit to evaluate outcomes and overall experience with the interventions.

Researchers are investigating upper-extremity proprioception impairment in patients experiencing radicular neuropathic symptoms caused by cervical disc herniation. This study focuses on the specific subgroup of cervical radiculopathy, which has not been systematically examined before, aiming to better understand the relationship between proprioceptive deficits and clinical outcomes such as pain and functional status. The study compares patients aged 18 to 65 years with cervical radiculopathy to a healthy control group matched by age, sex, and body mass index. Proprioception is assessed using the PRO-Reach method, which measures multisensory spatial representation of the entire upper limb through multiplanar and multi-joint evaluations without the need for computerized or robotic devices. Participants undergo baseline assessments including the Upper Limb Proprioception Reaching Test (PRO-Reach), pain rating scales (Numeric Rating Scale and DN-4 Questionnaire), quality of life evaluation (SHORT FORM-12), handgrip strength testing, and disability questionnaires (Quick Disabilities of the Arm, Shoulder and Hand Questionnaire). These measures help researchers evaluate sensory-motor function and its impact. The study involves healthy volunteers and patients, with data collection focused on initial measurements before any treatments, and participation is expected to last during the baseline assessment period.