Bursitis

Calcific tendinitis of the shoulder is a common condition involving calcium deposits in the rotator cuff tendons, often causing pain and functional issues. While many classification systems exist, they do not directly guide treatment or prognosis. This study aims to create a new, practical classification based on MRI localization of the deposits, and to explore how this classification relates to the treatments patients receive. The study reviews MRI scans and clinical records from patients treated for calcific tendinitis between 2004 and 2025. Patients are categorized into five groups according to where the calcium deposits are located on MRI outside the tendon, inside near the joint side, inside near the bursal side, completely within the tendon, or extending into the bone. Treatments include conservative non-surgical methods like pain relief and rest, or surgical interventions such as removal of the deposit and tendon repair techniques. Participants medical records, operative notes, and treatment details are examined to see how treatment relates to the new classification. The main outcome measured is the change in shoulder function and pain scores from before treatment to 12 months after surgery. This observational study involves reviewing existing patient data to understand the link between deposit location and treatment outcomes over time.

Researchers are evaluating the long-term outcomes of the ACE Acetabular Cup System, a device used in total hip replacement surgery. This procedure replaces both the hip ball and socket to relieve pain and help patients return to normal activities. The study aims to monitor the safety and performance of this CE-marked device over 10 years by assessing clinical, functional, and radiological results in patients with hip disease. The ACE Acetabular Cup System offers three options for socket liners ceramic, polymer, or dual mobility, allowing surgeons to choose the best fit for each patient. Participants in the study have received a primary elective total hip replacement using this system combined with a JRI femoral stem and head. The study is observational and follows patients over a decade to gather data on device function and patient health. Participants will be followed through questionnaires, reviews of X-rays, and monitoring of any complications. Key measurements include the Oxford Hip Score at 3 years post-operation, along with implant survivorship and other hip function assessments at multiple time points up to 10 years. Radiological assessments will also be conducted at 1, 5, and 10 years. This comprehensive follow-up helps researchers understand how well the device performs long-term and supports patient safety.

Researchers are investigating whether using a 10% benzoyl peroxide BPO acne cleanser before arthroscopic rotator cuff repair surgery can reduce contamination by Cutibacterium acnes, a common bacteria that can remain after standard sterilization. Although prior studies showed the bacteria can persist in up to 30% of cases despite cleaning, evidence specifically for rotator cuff surgery is limited. This study aims to provide clear guidance on improving preoperative skin preparation for this type of shoulder surgery. Participants will be randomly assigned to one of two groups. The control group will cleanse the surgical area with soap or body wash following current routine practices. The experimental group will receive a 10% BPO acne cleanser and instructions to use it on the shoulder and surrounding skin during bathing the day before surgery. After surgical disinfection, skin samples and segments of surgical sutures will be collected for bacterial culture to compare contamination rates between groups. During the study, patients will follow preoperative skin cleansing instructions according to their assigned group. Researchers will collect skin and suture samples right after surgery to assess bacterial presence. The primary measurement is the bacterial culture result from sutures immediately after surgery. This prospective randomized design will help determine if BPO cleansing effectively lowers contamination and may influence future surgical preparation practices. Participation lasts through surgery and immediate postoperative sampling.

Researchers are investigating the role of acupuncture in managing pain and improving outcomes after total knee replacement surgery TKA for patients with primary osteoarthritis. This study aims to assess whether acupuncture can help control acute pain, prevent chronic pain, improve joint function, and increase patient satisfaction. The research also examines how acupuncture influences inflammation by measuring specific biomarkers, which may relate to recovery and long-term joint stiffness. Participants will receive standard anesthesiology care including sedation, regional nerve blocks, and pain medications. They will be randomly assigned to either a standard treatment group or an acupuncture group, which receives additional acupuncture and auriculotherapy sessions before and after surgery. The acupuncture treatment targets specific body and ear points over multiple sessions during the first three days post-surgery. Throughout the study, participants will be monitored regularly for pain levels, medication use, vital signs, joint mobility, and rehabilitation progress. Blood samples will be taken before surgery and at set intervals afterward to measure inflammation markers. Patient-reported outcomes and satisfaction will be collected up to one year post-surgery. Evaluations will be done in person or by phone if necessary, with the entire follow-up extending through one year after the operation.

Researchers are evaluating the additional effects of combining mobilization with movement and upper quadrant core strengthening in people experiencing rotator cuff related shoulder pain. This randomized controlled trial aims to determine how these treatments impact pain, range of motion, proprioception, and fear of movement kinesiophobia. Participants are randomly assigned to one of two groups. One group performs an upper quadrant core strengthening protocol over four weeks, including scapular postural correction, shoulder shrugging, and rotation exercises. The other group performs the same strengthening protocol combined with mobilization techniques involving acromioclavicular, scapular, and glenohumeral joint glides. During the study, participants will have their pain intensity, shoulder range of motion, proprioception, and kinesiophobia measured after four weeks. Data collection includes assessments before and after treatment, and participants provide informed consent before enrollment. The study runs from July 2024 to June 2025.

Researchers are comparing three types of nerve blocks used for managing pain after shoulder arthroscopic surgeries. The study focuses on anterior glenoid nerve block, pericapsular nerve group PENG block, and interscalene brachial plexus ISB block. These blocks help reduce postoperative pain, improve patient comfort, speed up rehabilitation, and potentially shorten hospital stays. ISB blocks are well known as the standard method, while the PENG block is a newer technique that may provide pain relief with fewer side effects and quicker movement recovery. Participants will be randomly assigned to receive one of the three nerve blocks the interscalene brachial plexus block, the anterior glenoid nerve block, or the pericapsular nerve group PENG block. All blocks are applied using ultrasound guidance during shoulder arthroscopic surgery. The study is double-blinded, meaning neither patients nor doctors know which block is given to ensure unbiased results. During the study, researchers will monitor the time until patients need their first rescue pain medication within 24 hours after surgery. They will also track total opioid use, pain levels, hospital stay duration, time to freely move the operated shoulder, and patient satisfaction. These measures help assess each blocks effectiveness and safety. The entire study includes follow-up up to one week after surgery to observe recovery progress and potential complications.

This research aims to evaluate the safety of using allogeneic umbilical cord-derived mesenchymal stem cells in patients undergoing arthroscopic rotator cuff repair for large to massive rotator cuff tears. It focuses on adults aged 19 and older who have significant shoulder pain and full-thickness tears that have not improved with conventional treatments. The study is sponsored by Korea University Anam Hospital and is designed to assess pain and tissue healing over a year. Participants receive a single injection of allogeneic umbilical cord-derived mesenchymal stem cells during their rotator cuff repair surgery. Two dosing options are studied a low dose of 2.5x10 cells in 0.5 mL and a high dose of 5x10 cells in 1 mL. The injection is performed into the lesion using ultrasound guidance by the investigator. This treatment is given only once during the study period. Throughout the 12 months following treatment, participants will be monitored for pain during movement using the Visual Analog Scale VAS and changes in the size of their rotator cuff tears through MRI scans. Adverse events will also be tracked to assess safety. Participants will complete questionnaires and attend regular follow-up visits during the study. The total duration of participation spans one year from the intervention.

Researchers are evaluating whether artificial intelligence AI can help doctors detect broken bones, joint effusions, dislocations, and bone lesions more quickly and accurately in emergency room settings. This prospective, randomized, controlled trial compares traditional diagnostic methods to AI-assisted X-ray interpretation. The study also aims to see if AI can save time and reduce healthcare costs while improving clinical workflows in orthopedic emergency care. Participants will be assigned to one of two groups one using standard physician interpretation of X-rays without AI assistance, and the other using AI tools Aidoc or Gleamer BoneView integrated into the hospitals imaging system to highlight potential injuries in real time. Both groups will receive standard X-ray imaging of injured arms or legs. The AI serves as a diagnostic aid, with physicians making final diagnoses. The study includes around 4,800 patients presenting with isolated extremity injuries or joint complaints. During the study, participants will undergo routine X-ray imaging and have their images reviewed with or without AI support depending on group assignment. Researchers will collect baseline demographic and clinical data and assess diagnostic accuracy, time to diagnosis, physician confidence, and cost efficiency. Diagnoses will be independently reviewed by experts to ensure accuracy. The study adheres to ethical guidelines and requires informed consent from participants. Results may inform future use of AI in emergency care settings.

Researchers are studying how daily changes in mood, pain, and activity relate to acute and chronic pain using a smartphone app called SOMA. The study includes people with acute pain, chronic pain, and healthy controls. A smaller sub-study focuses on patients with chronic low back pain, failed back surgery syndrome, or fibromyalgia, using EEG testing to explore brain and behavior patterns that might predict treatment responses. Participants will use the SOMA app daily for four months to track their symptoms and activities. Those in the sub-study will also attend an in-person EEG session to perform specific tasks before starting app use. Data collected will help identify patterns linked to pain transition, recovery, or flare-ups. The study also monitors app engagement and symptom dynamics over up to 12 months. During the study, participants will report pain, mood, and activity daily through the app. Researchers will analyze these reports alongside baseline and follow-up EEG and behavioral tests. Outcomes include measuring the likelihood of acute pain becoming chronic and understanding mood and pain interactions. Participants progress and app usage will be observed over time to assess feasibility and treatment effects.

This clinical trial studies two groups in rural settings healthcare personnel and patients with shoulder pain lasting more than six months. The research aims to assess how usable and satisfying the TRAK tele-rehabilitation tool is for both groups. The study seeks to compare this digital approach with conventional rehabilitation exercises typically done at home. Patients with shoulder pain will be randomly assigned to either use the TRAK platform for eight weeks or follow a paper-based exercise protocol based on usual care. Healthcare professionals will use the TRAK tool throughout the study to prescribe exercises, monitor progress, and communicate with patients. Exercise frequency is personalized by healthcare providers, ranging from 3 to 7 days per week. Participants will complete quality of life and shoulder function assessments at the start and end of the study. Researchers will also gather feedback on the telemedicine usability and satisfaction after eight weeks. The study includes baseline health assessments, questionnaires, and a final face-to-face visit to evaluate outcomes and overall experience with the interventions.