Actively Recruiting

Age: 16Years - 80Years
All Genders
Healthy Volunteers
NCT03030755

Corneal Elastography and Patient Specific Modeling

Led by The Cleveland Clinic · Updated on 2025-10-22

60

Participants Needed

1

Research Sites

521 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

The goal of this research is to develop measurement tools and simulation technology for characterizing and predicting individual responses to corneal treatments and for advancing understanding of corneal ectasia risk factors. Patients who either 1) have keratoconus and are being evaluated for corneal crosslinking or 2) have refractive error and are being evaluated for refractive surgery procedures such as LASIK will have their eyes imaged to assess their mechanical properties and will have computational simulations performed to predict the response to treatment. One aim of the study is to test the hypothesis that computational models can predict the cornea's shape changes within clinically acceptable limits of error.

CONDITIONS

Official Title

Corneal Elastography and Patient Specific Modeling

Who Can Participate

Age: 16Years - 80Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Patients diagnosed with keratoconus based on standard criteria such as topographic steepness and irregular astigmatism consistent with keratoconus
  • Patients who are candidates for LASIK (laser vision correction) surgery and scheduled for the procedure
Not Eligible

You will not qualify if you...

  • Unable to provide informed consent, including non-English speakers without an interpreter or cognitively/mentally impaired individuals without a legal guardian

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Cleveland Clinic Foundation Cole Eye Institute

Cleveland, Ohio, United States, 44195

Actively Recruiting

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Research Team

P

Pamela Hoffman, MS

CONTACT

R

Rachel Rusnak

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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