Study of Corneal Elastography and Patient-Specific Modeling to Predict Corneal Treatment Outcomes

What this Trial Is About

Researchers are studying corneal biomechanical properties to better understand and predict individual responses to corneal treatments. This observational study focuses on patients with keratoconus being evaluated for corneal crosslinking and patients with refractive errors being considered for refractive surgery such as LASIK. The goal is to develop tools and simulations that characterize corneal strength and help identify risk factors for corneal ectasia, a serious cause of vision problems worldwide. Participants will undergo imaging using an optical coherence tomography OCT system to assess the mechanical condition of their corneas. Computational models of each eye will be created from these images, and simulations of the planned treatments will be performed to predict how the cornea will change shape. No additional procedures beyond imaging are involved in this study. During the study, participants will have their eyes imaged and data collected to compare predicted corneal responses with actual treatment outcomes. Researchers will evaluate the accuracy of these computational models three months after surgery. The total participation time varies, and safety monitoring includes ensuring informed consent and understanding participant eligibility. The study is open to a broad age range of adults and includes those planning to undergo corneal treatments or surgery.

Corneal Elastography and Patient Specific Modeling