Actively Recruiting
Study of Heart Risk Markers in Adults with Rheumatoid Arthritis Using Coronary Artery Calcium and Troponin Tests
Led by Brigham and Women's Hospital · Updated on 2026-07-14
120
Participants Needed
3
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
This research aims to identify biomarkers that help predict heart disease risk in people with rheumatoid arthritis RA. Individuals with RA have up to double the risk of heart attack compared to those without RA. The study focuses on adults who are not currently recommended for lipid-lowering therapy by standard risk calculators but may still be at risk. Participants will have their blood tested for high sensitivity cardiac troponin hs-cTn and undergo a coronary artery calcium CAC scan. These tests are evaluated to see if they better classify heart risk in RA patients who might benefit from early preventive treatment. The study observes patients without administering any treatments. During the study, participants undergo baseline measurements including blood tests and CAC scans. The primary outcome assessed is the coronary artery calcium score at baseline, which helps evaluate the extent of calcified plaque in the arteries. The study runs until March 2028, with ongoing observation but no specified treatment period, focusing on collecting data to improve heart risk assessment in RA.
CONDITIONS
Brief Title
The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study
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