Actively Recruiting

Age: 19Years +
All Genders
NCT05272618

Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries

Led by Chonnam National University Hospital · Updated on 2026-05-12

150

Participants Needed

1

Research Sites

463 weeks

Total Duration

On this page

Sponsors

C

Chonnam National University Hospital

Lead Sponsor

K

Korean Cardiac Research Foundation

Collaborating Sponsor

AI-Summary

What this Trial Is About

To compare clinical outcomes of myocardial infarction with non-obstructive coronary arteries (MINOCA) according to the coronary microvascular dysfunction (CMD), evaluated by optical coherence tomography (OCT), invasive and non-invasive coronary physiologic assessment.

CONDITIONS

Official Title

Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries

Who Can Participate

Age: 19Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Age 19 years or older with acute myocardial infarction
  • Rise and/or fall of cardiac troponin above 99th percentile plus ischemic signs or symptoms
  • Non-obstructive coronary arteries with less than 50% diameter narrowing or fractional flow reserve (FFR) above 0.80
  • No previous history of coronary artery disease
  • Underwent invasive coronary angiography within 24 hours of symptom onset
  • Eligible for invasive and non-invasive coronary physiologic assessments
Not Eligible

You will not qualify if you...

  • Obstructive coronary arteries
  • Alternate diagnoses including sepsis, pulmonary embolism, myocarditis, Takotsubo syndrome, spontaneous coronary dissection, and other cardiomyopathies
  • Cardiogenic shock or cardiac arrest
  • Non-cardiac conditions with life expectancy less than 1 year
  • Pregnant or lactating women
  • Unable to provide consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Chonnam National University Hospital

Gwangju, Gwangju, South Korea, 61469

Actively Recruiting

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Research Team

Y

Young Joon Hong, MD, PhD

CONTACT

S

Seung Hun Lee, MD, PhD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Coronary Microvascular Dysfunction Assessments in Myocardial Infarction With Non-Obstructive Coronary Arteries | DecenTrialz