Actively Recruiting
The Impact of Anxiety, Stress and Pain in the Early Phase of Myocardial Infarction on the Development of Anxiety Symptoms and Posttraumatic Stress Disorder in the Long Term Outcome
Led by Medical University of Graz · Updated on 2025-09-29
100
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This research aims to understand how anxiety, stress, and pain experienced during a heart attack (myocardial infarction) may lead to long-term psychological effects such as posttraumatic stress disorder (PTSD). The study focuses on detecting the percentage of people who develop anxiety, stress, and PTSD symptoms after an acute heart attack. PTSD is also noted as a risk factor for further heart disease, making this research important for prevention and care. Participants include adults aged 19 to 90 who have had a myocardial infarction. They will be observed at three key times: within the first 1 to 3 days of their heart attack, before leaving the hospital (5 to 14 days), and again after 6 months for follow-up. During these times, participants will complete questionnaires about their stress, anxiety, and well-being. Blood samples will be taken to measure stress hormones like cortisol and metanephrine. Clinical tests including lab runs, ECGs, and echocardiograms will also be performed to monitor heart function. Participants will be assessed through questionnaires, cognitive tests, blood tests, and heart evaluations at each visit to track changes over time. The main outcome is to measure PTSD symptoms six months after the heart attack. The study aims to better understand the biological, psychological, and social factors involved to improve prevention strategies. Total participation includes initial hospital assessments and a six-month follow-up.
CONDITIONS
Brief Title
Anxiety, Stress and Pain & Myocardial Infarction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Willingness to participate in the study
- Men and women aged 19 to 90
- Recent myocardial infarction
- No psychiatric disease before myocardial infarction
- No severe disease affecting the immune system
You will not qualify if you...
- Not meeting inclusion criteria
- Non-compliant patients (e.g., dementia, delirium)
- Receiving steroid therapy
AI-Screening
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Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - Up to 2 weeks
Participants are screened for eligibility to participate in the trial.
Initial assessments occur during hospital admission for myocardial infarction
Duration - Day 1 to Day 14 after myocardial infarction
Participants undergo clinical evaluations, laboratory tests, ECGs, echocardiographies, and cognitive testing to assess their condition during the acute myocardial infarction phase.
3 visits (Day 1-3, Day 5-14, in-person)
Duration - Up to 6 months following myocardial infarction
Participants complete questionnaires and undergo assessments to monitor anxiety, stress, PTSD symptoms, cognitive abilities, and biological stress markers over time.
1 follow-up visit at 6 months (in-person)
Trial Site Locations
Total: 1 location
1
Medical University of Graz
Graz, Styria, Austria, 8036
Actively Recruiting
Research Team
A
Andreas Baranyi, MD
H
Hans-Bernd Rothenhäusler, MD
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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