Actively Recruiting

All Genders
ID04263935

Correlation Between Driver Gene Abnormalities and Clinicopathological Characteristics and Disease Prognosis in Lymphoma

Led by Henan Cancer Hospital · Updated on 2025-04-23

200

Participants Needed

1

Research Sites

26 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are conducting a prospective non-interventional observational study to explore the relationship between driver gene abnormalities and the clinical characteristics and prognosis of lymphoma in Chinese patients. The study aims to collect detailed data on genetic changes, demographic and pathological features, and treatment outcomes to understand how these factors correlate with disease progression and treatment response. Participants diagnosed with lymphoma according to WHO 2017 criteria are included in this study. There are no specific treatment interventions as this is an observational study. Data collection focuses on genetic abnormalities and clinical features without altering standard patient care. Participants will have their gene abnormalities and clinical features monitored over time, with outcomes such as the incidence of driver gene abnormalities assessed up to 36 months. Researchers will also evaluate the objective response rate and 5-year overall survival. The study involves collecting demographic and treatment data to analyze disease prognosis and treatment efficacy over a long-term follow-up period.

CONDITIONS

Brief Title

Correlation Between Driver Gene Abnormalities and Clinicopathological Characteristics and Disease Prognosis in Lymphoma

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosed as lymphoma (according to WHO 2017 classification criteria)
  • Life expectancy no less than 3 months
  • Agreeing to sign the written informed consents
Not Eligible

You will not qualify if you...

  • Other malignant tumor history or active malignant tumor need be treated
  • Researchers determine unsuited to participate in this trial

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Monitoring

Duration - Up to 5 years

Participants with lymphoma are observed to collect data on driver gene abnormalities, clinicopathological characteristics, treatments, and disease prognosis.

Trial Site Locations

Total: 1 location

1

Henan Cancer Hospital/The affiliated Cancer Hospital of ZhengZhou university

Zhengzhou, Henan, China

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Research Team

Y

Yanyan Liu, M.D. Ph.D

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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