Actively Recruiting
Led by The Third Xiangya Hospital of Central South University · Updated on 2024-11-01
200
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are exploring the connection between blood serum renalase levels and microcirculation obstruction in patients who have experienced an acute myocardial infarction (AMI) and undergone primary percutaneous coronary intervention (PCI). The goal is to identify possible risk factors for microcirculation obstruction in these patients. This observational study is sponsored by The Third Xiangya Hospital of Central South University and focuses on acute heart attack patients treated with emergency PCI. Participants must have had a STEMI heart attack within 12 hours or between 12 to 48 hours if persistent ischemic symptoms, hemodynamic instability, or life-threatening ventricular arrhythmias are present. High-risk NSTEMI patients undergoing emergency PCI may also be included. The study involves observing patients after their PCI treatment without introducing new interventions. During the study, researchers will monitor participants using contrast-enhanced magnetic resonance imaging (MRI) conducted 3 to 7 days after PCI to assess microvascular obstruction. The study will track the number of patients showing this condition. Participants will provide consent and be followed to collect data relevant to renalase levels and heart microcirculation. The total study period extends until October 2025, starting from August 2024.
CONDITIONS
Correlation of Blood Serum Renalase and Microcirculation Obstruction in Patients with Acute Myocardial Infarction After Primary Percutaneous Coronary Intervention
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - 3 to 7 days after primary percutaneous coronary intervention
Participants undergo contrast-enhanced magnetic resonance imaging to assess microvascular obstruction.
1 visit (in-person)
Total: 1 location
1
The Third Xiangya Hospital of Central South University
Changsha, Hunan, China, 410013
Actively Recruiting
W
Weihong Jiang
Y
Ye Chen
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Ye Chen, Ruixuan Li, Ru Fu...
https://pubmed.ncbi.nlm.nih.gov/41314850