Actively Recruiting
Study of Brain Activity in Cortical-Basal Ganglia Networks During Speech in Adults Undergoing Deep Brain Stimulation Surgery for Parkinsons Disease, Essential Tremor, or Dystonia
Led by Massachusetts General Hospital · Updated on 2026-03-25
80
Participants Needed
1
Research Sites
N/A
Total Duration
AI-Summary
What this Trial Is About
Researchers are studying brain activity related to speech perception and production in neurological diseases that affect the basal ganglia, such as Parkinsons disease, essential tremor, and dystonia. The study aims to understand how neural activity in the cortical-basal ganglia circuits controls speech production during deep brain stimulation DBS surgery. Participants will undergo electrophysiological data collection during their DBS implantation surgery. This involves recording brain signals to analyze speech-related neural activity. The study focuses on collecting interpretable speech-related data during the single DBS surgery procedure. During the study, participants will provide brain signal data at the time of their DBS surgery. Researchers will measure the number of subjects from whom interpretable speech-related electrophysiological data can be collected. Participants must be able to consent and follow instructions, and the study includes adults aged 18 to 85 years. The total participation time corresponds to the duration of the DBS surgery.
CONDITIONS
Brief Title
Cortical-Basal Ganglia Speech Networks
Research Team
M
Mark Richardson, MD, PhD
E
Erin Donahue, PhD
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