Actively Recruiting
Cortical-Basal Ganglia Speech Networks Study Using Electrophysiological Data Collection During Deep Brain Stimulation Surgery
Led by Massachusetts General Hospital · Updated on 2026-03-25
80
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are studying brain activity related to speech perception and production in neurological diseases that affect the basal ganglia, such as Parkinson's disease, essential tremor, and dystonia. The study aims to understand how neural activity in the cortical-basal ganglia circuits controls speech production during deep brain stimulation (DBS) surgery. Participants will undergo electrophysiological data collection during their DBS implantation surgery. This involves recording brain signals to analyze speech-related neural activity. The study focuses on collecting interpretable speech-related data during the single DBS surgery procedure. During the study, participants will provide brain signal data at the time of their DBS surgery. Researchers will measure the number of subjects from whom interpretable speech-related electrophysiological data can be collected. Participants must be able to consent and follow instructions, and the study includes adults aged 18 to 85 years. The total participation time corresponds to the duration of the DBS surgery.
CONDITIONS
Brief Title
Cortical-Basal Ganglia Speech Networks
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Scheduled for DBS implantation with a confirmed diagnosis of Parkinson's disease, essential tremor, or dystonia
- Able to provide informed consent and follow task instructions
- Age between 18 and 85 years
You will not qualify if you...
- Reported hearing loss
- Non-English-speaking individuals
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Duration of single DBS surgery
Participants undergo deep brain stimulation surgery during which electrophysiological data related to speech production are collected.
1 surgery day (in-person)
Trial Site Locations
Total: 1 location
1
Massachusetts General Hospital
Boston, Massachusetts, United States, 02114
Actively Recruiting
Research Team
M
Mark Richardson, MD, PhD
E
Erin Donahue, PhD
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
BASIC_SCIENCE
Number of Arms
1
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