Actively Recruiting

Phase Not Applicable
Age: 18Years - 60Years
All Genders
Healthy Volunteers
NCT05256160

Cortical Excitability in Cyclic Vomiting Syndrome

Led by University of Pittsburgh · Updated on 2025-08-24

110

Participants Needed

1

Research Sites

263 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This exploratory study will determine if there are differences in cortical excitability between patients suffering from cyclic vomiting syndrome (CVS) and healthy control subjects, as assessed by a non-invasive method of brain stimulation (Transcranial Magnetic Stimulation, TMS).

CONDITIONS

Official Title

Cortical Excitability in Cyclic Vomiting Syndrome

Who Can Participate

Age: 18Years - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Diagnosis of cyclic vomiting syndrome (CVS)
Not Eligible

You will not qualify if you...

  • History of CVS for healthy control participants only
  • Psychosis or altered cognitive status
  • History of head injury, metal in the skull, stroke, seizures, or syncope (fainting or passing out)
  • Use of implantable devices such as pacemaker or nerve stimulator
  • Current use of medications or substances that lower seizure threshold including clozapine, chlorpromazine, amphetamines, methamphetamine, Ecstasy, Ketamine, PCP, cocaine, or consumption of 3 or more alcoholic drinks per day
  • Pregnancy

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of Pittsburgh Medical Center

Pittsburgh, Pennsylvania, United States, 15232

Actively Recruiting

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Research Team

P

Paul HM Kullmann, PhD

CONTACT

D

David J Levinthal, MD PhD

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NON_RANDOMIZED

Model

PARALLEL

Primary Purpose

BASIC_SCIENCE

Number of Arms

2

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