Actively Recruiting
Creation of a French South-Eastern Database and DNA-bank of Congenital Heart Disease to Explore the Genetic Pathways
Led by Assistance Publique Hopitaux De Marseille · Updated on 2023-03-13
300
Participants Needed
1
Research Sites
580 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Congenital heart defects are seen in 0,8% of life births. In France this means more than 5000 newborns per year. The south-east region of France is particularly affected as a result of a higher birth rate and consanguinity, when compared to other regions. The majority of congenital heart diseases remain unexplained. Genetic causes are indisputable but remain poorly understood. Genetic research needs the availability of a large-scale DNA collection, guided by a robust phenotypic classification. Such a DNA-bank has been created in Paris (CARREG DNA bank, created by the M3C reference centre for congenital heart diseases). Such a bank is currently unavailable in south-east France. To transport biological specimens from Marseille to Paris would be very expensive. In addition, the whole infrastructure required for correct diagnosis and classification of the congenital heart diseases, for sampling, for storage of the samples and genetic analysis, does exist in our AP-HM hospital and in our AMU research unit. For those reasons it is highly preferable to elaborate such a database and DNA-bank locally. The acronym SEA-HD (South-EAst-Heart-Diseases) would be used to name this DNA-bank
CONDITIONS
Official Title
Creation of a French South-Eastern Database and DNA-bank of Congenital Heart Disease to Explore the Genetic Pathways
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Echocardiographic diagnosis of congenital heart defect falling within the classification Houyel and Bonnet
- Necessity of making a blood test regardless of study
- Medical care in the AP-HM Timone Hospital children, medical-surgical unit of pediatric and congenital cardiology, Marseille - These Parent Child
You will not qualify if you...
- Pregnant women
- Patients or parent / legal guardian (if minor) in physical or mental incapacity to understand or sign the consent
- People in Emergencies
- Persons deprived of freedom
- Persons not beneficiaries of a social security scheme
- Persons in health or social institution
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Assistance Publique Hopitaux de Marseille
Marseille, France, 13354
Actively Recruiting
Research Team
C
CAROLINE OVAERT
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
NA
Model
SINGLE_GROUP
Primary Purpose
DIAGNOSTIC
Number of Arms
1
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