Actively Recruiting

Age: 18Years - 60Years
All Genders
Healthy Volunteers
NCT03307330

A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea

Led by Mayo Clinic · Updated on 2026-02-13

120

Participants Needed

1

Research Sites

620 weeks

Total Duration

On this page

Sponsors

M

Mayo Clinic

Lead Sponsor

N

National Heart, Lung, and Blood Institute (NHLBI)

Collaborating Sponsor

AI-Summary

What this Trial Is About

Studies show that sleep apnea increases the risk of cardiovascular disease and is associated with obesity. However, it is unclear how sleep apnea affects fat tissue. Studies have shown that fat tissue is likely involved in developing cardiovascular disease. The purpose of this study is to see how sleep apnea changes fat tissue.

CONDITIONS

Official Title

A Cross-sectional Study Examining Adipose Tissue in Obstructive Sleep Apnea

Who Can Participate

Age: 18Years - 60Years
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • BMI 40 kg/m2
  • Not a current smoker or tobacco user
  • Individuals with treated hypertension, prehypertension, and dyslipidemia are allowed
  • No prescription medications except those for asthma, allergies, depression, acid reflux, topical skin treatments, shampoos, contraceptives, or intrauterine devices
  • Not pregnant or breastfeeding and not planning to become pregnant or breastfeed
  • Ability to provide written informed consent
  • If on aspirin or anti-inflammatory medication, must suspend use for 7 days before participation unless contraindicated by vascular disease
Not Eligible

You will not qualify if you...

  • Vulnerable study populations excluded
  • Chronic kidney disease (creatinine >2.5 mg/dL) or active cancers
  • Pregnancy
  • Anemia (hemoglobin <12 g/dL for men, <11 g/dL for women)
  • Current smoking
  • Use of chronic medications like statins, anti-inflammatory drugs, ARBs, or ACE inhibitors
  • Blood or plasma donation in the past 2 months

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Mayo Clinic

Rochester, Minnesota, United States, 55901

Actively Recruiting

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Research Team

S

Somers_CPL Lab

CONTACT

V

Virend Somers, MD., Ph.D

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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