Actively Recruiting

Age: 20Years +
All Genders
NCT06508697

CT-Angiography Plaque Characteristics and Events in Deferral Patients by Invasive Fractional Flow Reserve

Led by Fujita Health University · Updated on 2025-01-03

400

Participants Needed

1

Research Sites

100 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Fractional flow reserve (FFR)-guided PCI for chronic coronary syndromes (CCS) is reported to improve the outcomes compared with angiography-guided PCI. However, cardiac-events still occur in FFR-deferral patients in long-term follow-up. Coronary computed tomography angiography (CTA)-defined high-risk-plaque (HRP) is known to relate future cardiac events. The investigators hypothesized that CTA might identify plaque features linked to future cardiac events in deferral patients.

CONDITIONS

Official Title

CT-Angiography Plaque Characteristics and Events in Deferral Patients by Invasive Fractional Flow Reserve

Who Can Participate

Age: 20Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Men and women aged 20 years or older
  • Patients diagnosed with chronic coronary syndromes (CCS)
  • Coronary computed tomography angiography (CTA) performed within 90 days before invasive coronary angiography (ICA) with fractional flow reserve (FFR) measurement
Not Eligible

You will not qualify if you...

  • History of coronary bypass grafting (CABG)
  • Presence of left-main coronary artery disease
  • Fractional flow reserve (FFR) measured in stented vessels due to inability to assess plaque by CTA

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Fujita Health University

Toyoake, Aichi-ken, Japan, 470-1192

Actively Recruiting

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Research Team

Y

YUKIO OZAKI, MD, PhD

CONTACT

R

REINA OZAKI, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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