Actively Recruiting
D-SOLVE Cohorts (Cohort a and B)
Led by Hannover Medical School · Updated on 2025-03-12
750
Participants Needed
4
Research Sites
188 weeks
Total Duration
On this page
Sponsors
H
Hannover Medical School
Lead Sponsor
K
Karolinska University Hospital
Collaborating Sponsor
AI-Summary
What this Trial Is About
Hepatitis D is by far the most severe form of chronic viral hepatitis, frequently leading to liver failure, hepatocellular carcinoma and death. Hepatitis D is caused by coinfection Hepatitis D is caused by co-infection with hepatitis B virus (HBV) and hepatitis D virus (HDV). This multicenter cohort should enable a comprehensive and unbiased biomarker screening of well-defined HDV-infected patients, followed by mechanistic studies to determine the functional role of distinct molecules. Patient surveillance strategies and antiviral treatment approaches could be personalized which should reduce clinical and social disease burden, improve quality of life and save direct and indirect costs caused by HDV infection.
CONDITIONS
Official Title
D-SOLVE Cohorts (Cohort a and B)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Anti-HDV positive
- 18 years old or older
- Male, female, or diverse gender
- Provided informed consent for study procedures
You will not qualify if you...
- Anti-HDV negative
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 4 locations
1
Hannover Medical School, Department of Gastroenterology, Hepatology, Infectious Disease and Endocrinology
Hanover, Germany, 30625
Actively Recruiting
2
Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico (University of Milan)
Milan, Italy
Not Yet Recruiting
3
Institutul de Boli Infectioase "Prof. Dr. Matei Bals"
Bucharest, Romania, 021105
Actively Recruiting
4
Karolinska University Hospital and Karolinska Institutet
Stockholm, Sweden
Actively Recruiting
Research Team
P
Petra Dörge
CONTACT
J
Julia Kahlhöfer
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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