Actively Recruiting

All Genders
ID05454618

U-DECIDE: The Decision To Enroll In Therapeutic Clinical Trials In A Pediatric Cancer Clinical Network

Led by St. Jude Children's Research Hospital · Updated on 2026-05-20

400

Participants Needed

1

Research Sites

N/A

Total Duration

On this page

AI-Summary

What this Trial Is About

This research aims to understand the factors parents consider when deciding whether to enroll their child in therapeutic clinical trials within a pediatric cancer network. It focuses on describing the social and demographic characteristics of patients, assessing parents' attitudes and decision-making factors, and exploring how these relate to clinical trial enrollment. The study also evaluates a parent navigator program designed to support families during this decision process. Participants will complete surveys on demographics, social determinants, and attitudes toward clinical trials. Some parents will take part in qualitative interviews to discuss their experiences and preferences in depth. The study includes a pilot parent navigator program where trained parent navigators provide support and information to newly diagnosed families over a six-week period, with interactions via phone or text. Throughout the study, researchers will collect data from surveys, interviews, and program questionnaires to assess social factors, decision-making influences, and the acceptability and feasibility of the navigator program. Parent navigators will record contact details and complete evaluation forms, while parents will provide feedback on their satisfaction. The study outcomes include measuring sociodemographic traits, enrollment decisions related to social and attitudinal factors, and the effectiveness of the navigator support over approximately four years.

CONDITIONS

Brief Title

The Decision To Enroll In Therapeutic Clinical Trials In A Pediatric Cancer Clinical Network

Who Can Participate

All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Parent or legal representative of a child aged 0 to 18 years with newly diagnosed cancer
  • Ability to speak English or Spanish
  • Child is newly diagnosed and part of the Affiliate network
Not Eligible

You will not qualify if you...

  • Parent of a child with relapsed or recurrent cancer
  • Parent of a child with benign neoplasms

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (in-person or remote)

Survey Participation

Duration - Up to approximately 3 months

Participants complete surveys about sociodemographic characteristics, social determinants of health, decision-making factors, and attitudes toward clinical trial enrollment.

1 to 2 surveys administered verbally or electronically at mutually agreed times

Qualitative Interviews

Duration - Approximately 3 months after enrollment

A subset of participants participate in semi-structured interviews exploring their experiences and decision-making around clinical trial enrollment.

1 to 2 interviews conducted by phone or video conference

Parent Navigator Program

Duration - 6 weeks of navigator interaction with potential additional contacts as needed

Participants who enroll in a therapeutic clinical trial may engage with parent navigators for support and guidance during the initial 6 weeks post-enrollment.

Approximately 2 scheduled interactions plus additional contacts as necessary

Trial Site Locations

Total: 1 location

1

St. Jude Children's Research Hospital

Memphis, Tennessee, United States, 38105

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Research Team

D

Dylan Graetz, MD

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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