Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
NCT05452122

Decoding and Selective Modulation of Human Memory During Awake/Sleep Cycles

Led by University of California, Los Angeles · Updated on 2025-10-14

150

Participants Needed

1

Research Sites

215 weeks

Total Duration

On this page

Sponsors

U

University of California, Los Angeles

Lead Sponsor

U

University of Iowa

Collaborating Sponsor

AI-Summary

What this Trial Is About

The proposed project seeks to elucidate memory processes and consolidation during sleep by leveraging the unique capability of direct recordings from the human brain at multiple levels of resolution-single neurons, localized neuronal assemblies, intracranial local field potentials-during rich behavioral tasks with real-life narratives and extracting neural features that relate to different aspects of episodic experience. The investigators will further probe causal mechanisms of consolidation by application of auditory and electrical stimulations during sleep and its effect on modulating memory processes.

CONDITIONS

Official Title

Decoding and Selective Modulation of Human Memory During Awake/Sleep Cycles

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Adults aged 18 to 65 years
  • Diagnosed with epilepsy and undergoing depth electrode placement for clinical purposes
  • Eligibility determined by epilepsy surgery team based on neuropsychological and psychiatric evaluations
  • Willing to provide informed consent and participate in the study
Not Eligible

You will not qualify if you...

  • Any neurological or psychiatric conditions other than epilepsy that increase patient risk
  • Younger than 18 or older than 65 years of age
  • Unwilling to provide informed consent

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

University of California Los Angeles

Los Angeles, California, United States, 90095

Actively Recruiting

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Research Team

A

Andreina Hampton

CONTACT

How is the study designed?

Study Type

INTERVENTIONAL

Masking

SINGLE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

BASIC_SCIENCE

Number of Arms

0

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Decoding and Selective Modulation of Human Memory During Awake/Sleep Cycles | DecenTrialz