Actively Recruiting
Led by Lithuanian University of Health Sciences · Updated on 2025-12-16
300
Participants Needed
1
Research Sites
N/A
Total Duration
Researchers are studying hospitalized patients aged 18 to 85 years with chronic heart failure (CHF) to understand how common depressive symptoms and cognitive impairment are and how they relate to worse health outcomes. This observational study focuses on patients admitted due to worsening CHF and aims to determine if these mental health and cognitive issues lead to increased mortality or rehospitalizations. The study is conducted at a single center where most CHF patients in the region receive inpatient care. Participants who stabilize during their hospital stay will complete validated questionnaires assessing depression and cognitive function about 48 hours after stabilization and again at discharge. The questionnaires include the Patient Health Questionnaire-9 (PHQ-9), Hospital Anxiety and Depression Scale (HADS), and Montreal Cognitive Assessment (MoCA). Clinical data, treatments, and procedures during hospitalization will also be collected to explore how these factors relate to outcomes. During their participation, patients will undergo physical exams and provide demographic and clinical information. Researchers will track key outcomes such as death from any cause during and after hospitalization and CHF-related rehospitalizations over 12 months post-discharge. Data will be analyzed to identify links between depressive symptoms, cognitive impairment, and these health outcomes. The study aims to inform better screening and management of mental health and cognitive issues in CHF care.
CONDITIONS
Depressive Symptoms, Cognitive Impairment, and Outcomes in Hospitalized Chronic Heart Failure Patients
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Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person) during hospitalization after clinical stabilization
Duration - Approximately duration of the hospital stay, up to 30 days
Participants undergo assessments of depressive symptoms and cognitive function using standardized questionnaires during hospitalization.
2 visits (in-person) - one approximately 48 hours after stabilization and one on the last day of hospital stay
Duration - 12 months post discharge
Participants are followed for clinical outcomes including mortality and CHF-related rehospitalizations after hospital discharge.
Follow-up assessments occur up to 12 months after discharge; specific visit frequency not fixed
Total: 1 location
1
Kaunas Hospital of the Lithuanian University of Health Sciences
Kaunas, Lithuania, 47144
Actively Recruiting
A
Andrius Ališauskas, MD, PhD
K
Kornelija Dzikevičiūtė, MD
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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