Study of Depressive Symptoms and Cognitive Impairment and Their Impact on Outcomes in Adults Hospitalized for Chronic Heart Failure

What this Trial Is About

Researchers are studying hospitalized patients aged 18 to 85 years with chronic heart failure CHF to understand how common depressive symptoms and cognitive impairment are and how they relate to worse health outcomes. This observational study focuses on patients admitted due to worsening CHF and aims to determine if these mental health and cognitive issues lead to increased mortality or rehospitalizations. The study is conducted at a single center where most CHF patients in the region receive inpatient care. Participants who stabilize during their hospital stay will complete validated questionnaires assessing depression and cognitive function about 48 hours after stabilization and again at discharge. The questionnaires include the Patient Health Questionnaire-9 PHQ-9, Hospital Anxiety and Depression Scale HADS, and Montreal Cognitive Assessment MoCA. Clinical data, treatments, and procedures during hospitalization will also be collected to explore how these factors relate to outcomes. During their participation, patients will undergo physical exams and provide demographic and clinical information. Researchers will track key outcomes such as death from any cause during and after hospitalization and CHF-related rehospitalizations over 12 months post-discharge. Data will be analyzed to identify links between depressive symptoms, cognitive impairment, and these health outcomes. The study aims to inform better screening and management of mental health and cognitive issues in CHF care.

Depressive Symptoms, Cognitive Impairment, and Outcomes in Hospitalized Chronic Heart Failure Patients