Actively Recruiting

Age: 18Years +
All Genders
NCT04857528

Detecting HPV DNA in Anal and Cervical Cancers

Led by University of Chicago · Updated on 2026-03-04

20

Participants Needed

2

Research Sites

370 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

This is a research study for individuals who have cancer associated with human papillomavirus (HPV) and are being treated with radiation as part of standard care for their cancer. Doctors leading this study will use blood tests to find out if they can detect the HPV virus in the blood of study participants before, during, and after radiation treatment. They will also collect blood and archival tumor tissue (from a previous biopsy) to perform other tests in the future that could provide more information about HPV-associated cancers and how they respond to treatment. Participation in this study will last approximately 2 years.

CONDITIONS

Official Title

Detecting HPV DNA in Anal and Cervical Cancers

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Stage I-III anal cancer or stage I-IVA cervical cancer that tests positive for p16 by immunohistochemistry
  • Age 18 years or older
  • Planned to receive radiation therapy as the main treatment, with or without chemotherapy
Not Eligible

You will not qualify if you...

  • Anal carcinoma not linked to HPV types 16, 18, 31, 33, or 35
  • Planned to receive radiation therapy only after surgery or as additional treatment

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 2 locations

1

University of Illinois at Chicago

Chicago, Illinois, United States, 60612

Actively Recruiting

2

University of Chicago

Chicago, Illinois, United States, 60637

Actively Recruiting

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Research Team

C

Christina Son, MD

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

2

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Detecting HPV DNA in Anal and Cervical Cancers | DecenTrialz