Actively Recruiting
Detection and Management of Sinusitis in a Single-center Prospective Cohort of Patients With Exudative AMD (SINE)
Led by Fondation Ophtalmologique Adolphe de Rothschild · Updated on 2025-12-10
200
Participants Needed
1
Research Sites
271 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
An inflammatory component associated with AMD has been highlighted by genetic associations of predisposition to AMD, as well as by the recently demonstrated link between AMD and periodontitis. Some patients followed at the Fondation Adolphe de Rothschild Hospital for wet AMD seemed to show an improvement of neovascular activity (less need for intravitreal injections of anti-VEGF) after treatment of their sinusitis. The investigators would therefore like to assess the link between AMD and sinusitis, an infection close to the site of AMD.
CONDITIONS
Official Title
Detection and Management of Sinusitis in a Single-center Prospective Cohort of Patients With Exudative AMD (SINE)
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 18 years or older
- Treated for bilateral neovascular age-related macular degeneration for at least 2 years
- At least one eye received 6 or more intravitreal injections in the past year
- Provided consent to participate in the study
- Covered by a social security plan
You will not qualify if you...
- Pregnant or breastfeeding women, minors, persons under legal protection, or deprived of liberty
- Severe nearsightedness greater than 6 diopters
- Currently treated for acute or chronic sinusitis
- History of central serous chorioretinopathy or diffuse retinal epitheliopathy
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Hôpital Fondation A. de Rothschild
Paris, France, 75019
Actively Recruiting
Research Team
A
Amélie Yavchitz
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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