Actively Recruiting
Project AMD: Comprehensive Characterisation of Age-Related Macular Degeneration and Its Progression
Led by Center for Eye Research Australia · Updated on 2024-02-09
2500
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
Age-related macular degeneration (AMD) is a leading cause of irreversible vision loss worldwide, affecting millions including nearly two million Australians. Researchers aim to understand the causes of AMD, the differences in its types and severities, and how it progresses over time compared to healthy eyes. This observational study focuses on collecting detailed information about AMD’s characteristics, genetics, and patient experiences to better understand the disease. This study does not involve treatments but observes participants with AMD and those with normal age-related eye changes. It uses non-invasive eye imaging and functional tests to assess the retina, along with collecting biological samples and patient-reported outcomes. Participants include those with AMD and healthy controls, and the study will track AMD progression and associated factors over up to 20 years. Participants will undergo regular eye assessments, imaging, and provide biological samples during the study. Researchers will measure disease type, severity, genetic factors, and progression rates. The study also gathers patient feedback through questionnaires. This long-term follow-up will help identify how AMD develops and progresses, with all data collected under careful observation without intervention.
CONDITIONS
Brief Title
Project AMD: Comprehensive Characterisation of Age-Related Macular Degeneration and Its Progression
Who Can Participate
Eligibility Criteria
You may qualify if you...
- 18 years of age or older
- Diagnosis of age-related macular degeneration (AMD) with at least a medium druse larger than 63 micrometers
- Eyes with normal ageing changes including small drusen 63 micrometers or smaller or no abnormalities for control participants
You will not qualify if you...
- Presence of other eye or systemic conditions that could affect retinal assessment or AMD evaluation
- Any mental or physical impairment preventing informed consent or participation in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 20 years
Participants with Age-Related Macular Degeneration are observed over time to investigate the underlying causes and progression of their condition.
Periodic visits over the study duration
Trial Site Locations
Total: 1 location
1
Centre for Eye Research Australia
East Melbourne, Victoria, Australia, 3002
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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