Actively Recruiting

Phase Not Applicable
Age: 18Years +
All Genders
ID03976999

Development of a Prospective and Monocentric Clinical and Biological Database in Epithelial Ovarian, Fallopian Tube, and Primitive Peritoneal Cancers

Led by Institut du Cancer de Montpellier - Val d'Aurelle · Updated on 2025-02-12

300

Participants Needed

1

Research Sites

261 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are creating a clinical and biological database focused on epithelial ovarian cancer, fallopian tube cancer, and primitive peritoneal cancer. This database aims to gather blood and tissue samples along with clinical data to enhance scientific understanding and support the development of new cancer treatments. The study is designed to identify factors predicting treatment response, biological tumor markers linked to survival, and prognostic factors after cancer recurrence. Participants will have blood samples taken at multiple points: before treatment, after chemotherapy, after interval surgery, and upon cancer recurrence. Tissue samples from both tumor and healthy areas will be collected during surgery. Alongside these biological samples, standardized clinical information will be recorded in the database to support research. During the study, participants will provide informed consent and undergo sample collections as scheduled. Researchers will monitor the proportion of patients consenting to participate over three years. The study involves regular collection of clinical and biological data to advance understanding of these cancers and aid future research efforts. Participation includes sample collection at specific times related to treatment and surgery, with data securely stored for scientific use.

CONDITIONS

Brief Title

Development of a Cinical and Biological Database in Ovarian, Fallopian Tube and Peritoneal Cancers

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 years or older
  • Diagnosed with epithelial ovarian cancer, fallopian tube cancer, or primitive peritoneal cancer
  • Eligible for at least one surgery and chemotherapy
  • Provided informed, written, and express consent
Not Eligible

You will not qualify if you...

  • Not affiliated with a social protection scheme
  • Pregnant or nursing women
  • Under tutelage, curatorship, or safeguard of justice
  • Unable to attend regular follow-up due to psychological, familial, social, or geographical reasons

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Biological Sample Collection

Duration - Up to 3 years

Participants provide blood samples before treatment, after chemotherapy, after interval surgery, and after cancer recurrence. Tissue samples are collected during surgery. Clinical data is also collected and entered into a database.

4 visits corresponding to blood sample collections and surgery

Trial Site Locations

Total: 1 location

1

ICM - Institut régional du Cancer Montpellier

Montpellier, France, 34298

Actively Recruiting

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Research Team

A

Aurore MOUSSION

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

OTHER

Number of Arms

1

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Published Research Related To This Trial

Association between BRCA1 and BRCA2 mutations and survival in women with invasive epithelial ovarian cancer.

Kelly L Bolton, Georgia Chenevix-Trench, Cindy Goh...

https://pubmed.ncbi.nlm.nih.gov/22274685

Association of BRCA1 and BRCA2 mutations with survival, chemotherapy sensitivity, and gene mutator phenotype in patients with ovarian cancer.

Da Yang, Sofia Khan, Yan Sun...

https://pubmed.ncbi.nlm.nih.gov/21990299