Actively Recruiting
Development and Validation of Microbiota and Metabolite-based Prediction Model for Recurrence of High-risk Colorectal Polyps After Polypectomy
Led by Peking Union Medical College Hospital · Updated on 2025-07-01
150
Participants Needed
1
Research Sites
157 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
The characteristics of the intestinal microbiota in high-risk colorectal polyp recurrence and their relationship with disease pathogenesis have not yet been fully elucidated. This study aims to analyze the microbial community characteristics in the intestinal mucosal tissue of patients after polypectomy with recurrence of colorectal polyps. Additionally, this research holds significant importance for understanding the etiology of adenoma recurrence and develop a microbiota and metabolite-based predicting tool.
CONDITIONS
Official Title
Development and Validation of Microbiota and Metabolite-based Prediction Model for Recurrence of High-risk Colorectal Polyps After Polypectomy
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients aged 40 to 75 years
- Underwent colonoscopy with at least one advanced premalignant polyp or three or more adenomas
You will not qualify if you...
- Severe physical diseases preventing adherence to examination requirements
- Coagulopathy or other contraindications for biopsy or polypectomy
- Previous surgical procedures on the gastrointestinal tract
- Presence of colorectal cancer or other malignant tumor at baseline
- Presence of inflammatory bowel disease or hereditary polyposis syndromes such as familial adenomatous polyposis or Lynch syndrome
- Use of oral antibiotics or probiotics within 1 month before enrollment
- Inability to provide informed consent or refusal to participate in the study
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 1 location
1
Peking Union Medical College Hospital, 1 Shuaifuyuan, Dongcheng District, Beijing, China
Beijing, China, 100730
Actively Recruiting
Research Team
C
Cheng Peng, MD
CONTACT
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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