Actively Recruiting
DFC 004 Biomarkers for Active Diabetic Foot Ulcers
Led by University of Michigan · Updated on 2025-09-15
5000
Participants Needed
8
Research Sites
261 weeks
Total Duration
On this page
Sponsors
U
University of Michigan
Lead Sponsor
N
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Collaborating Sponsor
AI-Summary
What this Trial Is About
This study is a platform study designed to efficiently test multiple biomarkers to identify diabetic foot ulcers (DFUs) with a higher potential for healing versus not healing that ultimately could be applied at the point of care to drive personalized management decisions, and to better inform clinical trials of wound healing interventions
CONDITIONS
Official Title
DFC 004 Biomarkers for Active Diabetic Foot Ulcers
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Signed and dated informed consent form provided
- Age 18 years or older
- Clinically diagnosed with diabetes or meeting American Diabetes Association criteria
- Have an open foot ulcer from the ankle down, including post-surgical wounds healing by secondary intention
- Agree to follow study visits and provide required biospecimens and clinical data
You will not qualify if you...
- Participation in an interventional diabetic foot ulcer clinical trial within 1 month before first visit
- Currently receiving radiation or chemotherapy targeting the ulcer area
- Presence of gangrene in any part of the foot with the study ulcer
- Planned or under evaluation for revascularization of the affected limb within 4 weeks from study start
- Severe limb ischemia (SVS WIfl Ischemia grade 3)
- Any medical or psychiatric condition that could prevent safe completion of the study according to the investigator
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Trial Site Locations
Total: 8 locations
1
University of Arizona College of Medicine
Tucson, Arizona, United States, 85724
Actively Recruiting
2
University of Southern California
Los Angeles, California, United States, 90033
Active, Not Recruiting
3
University of California - San Francisco
San Francisco, California, United States, 94143
Actively Recruiting
4
Emory University School of Medicine
Atlanta, Georgia, United States, 30303
Actively Recruiting
5
Beth Israel Deaconess Medical Center
Boston, Massachusetts, United States, 02215
Actively Recruiting
6
University of Michigan
Ann Arbor, Michigan, United States, 48109
Actively Recruiting
7
Northwell Health
Lake Success, New York, United States, 11042
Actively Recruiting
8
University of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15219
Actively Recruiting
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
1
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