Actively Recruiting

Age: 18Years +
All Genders
Healthy Volunteers
NCT05405673

Diagnostic Accuracy of a Panel of Bacterial Gene Markers (M3) for Colorectal Advanced Neoplasia

Led by Chinese University of Hong Kong · Updated on 2024-08-27

2500

Participants Needed

1

Research Sites

183 weeks

Total Duration

On this page

Sponsors

C

Chinese University of Hong Kong

Lead Sponsor

D

Dr Cipto Mangunkusumo General Hospital

Collaborating Sponsor

AI-Summary

What this Trial Is About

The investigators aim to evaluate and compare the diagnostic accuracy of FIT and the novel panel of bacterial gene markers (Fn, m3, Ch and Bc) collectively named as M3, in detecting colorectal advanced neoplasia.

CONDITIONS

Official Title

Diagnostic Accuracy of a Panel of Bacterial Gene Markers (M3) for Colorectal Advanced Neoplasia

Who Can Participate

Age: 18Years +
All Genders
Healthy Volunteers

Eligibility Criteria

Eligible

You may qualify if you...

  • Require elective colonoscopy for colorectal cancer screening, polyp surveillance, or symptom investigation such as anemia, bowel habit changes, or abdominal pain
  • Aged 18 years or older
  • Able to provide written informed consent
Not Eligible

You will not qualify if you...

  • Contraindications to colonoscopy such as perforation, intestinal obstruction, or unstable heart/lung status
  • Contraindications to polyp removal like active gastrointestinal bleeding or ongoing anticoagulation or dual antiplatelet therapy
  • Known colorectal cancer or adenoma scheduled for staged procedure
  • Previous colon surgery
  • Personal history of colorectal cancer
  • Personal history of polyposis syndrome
  • Personal history of inflammatory bowel disease
  • Known pregnancy or breastfeeding
  • Advanced serious health conditions classified as American Society of Anesthesiologists grade 4 or higher

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Trial Site Locations

Total: 1 location

1

Prince of Wales Hospital

Hong Kong, Hong Kong

Actively Recruiting

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Research Team

C

Connie Seto

CONTACT

M

Min Dai

CONTACT

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

1

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Diagnostic Accuracy of a Panel of Bacterial Gene Markers (M3) for Colorectal Advanced Neoplasia | DecenTrialz