Evaluating Transcranial Doppler Ultrasound to Diagnose Brain Injuries in High-Risk Newborns

What this Trial Is About

Researchers are evaluating the use of transcranial Doppler ultrasonography TCD to diagnose brain injuries in newborns, especially those considered high-risk. High-risk neonates include infants with conditions such as neonatal sepsis, encephalopathy, respiratory distress, seizures, birth asphyxia, or other signs of central nervous system disorders. This observational study focuses on newborns up to 37 weeks old and aims to understand how well TCD can detect craniocerebral injuries in these vulnerable infants. The study involves two groups high-risk neonates with confirmed risk factors and healthy neonates matched by age and sex. Participants will undergo transcranial Doppler ultrasound, a noninvasive procedure performed at the bedside that measures blood flow velocity in key brain arteries. This device-based assessment provides real-time information about cerebral blood flow, complementing other imaging methods. The study will compare findings between high-risk and healthy neonates. During the study, participants will be monitored, and the primary outcome is the sensitivity of the transcranial Doppler ultrasound measured six months after the procedure. Researchers will observe and record blood flow data using duplex pulsed Doppler ultrasound. The study includes careful evaluation of the infants neurological status and clinical conditions. The total participation duration and follow-up details are aligned with the timing of the primary outcome measurement at six months post-assessment.

Diagnostic Value of Transcranial Doppler Ultrasound for Evaluating Neonatal Craniocerebral Injuries