Diuretics and salt restriction in blood pressure control.
Wassertheil-Smoller, H G Langford, M D Blaufox...
https://pubmed.ncbi.nlm.nih.gov/6342972Completed
Phase 3
Age: 40Years +
All Genders
ID00000497
Led by University of Mississippi Medical Center · Updated on 2015-04-15
N/A
Participants Needed
N/A
Research Sites
N/A
Total Duration
On this page
Sponsors
U
University of Mississippi Medical Center
Lead Sponsor
N
National Heart, Lung, and Blood Institute (NHLBI)
Collaborating Sponsor
AI-Summary
What this Trial Is About
The primary objective of this multicenter cooperative clinical trial was to determine if dietary modification would enable drug controlled hypertensive patients to remain at 'goal blood pressures' after antihypertensive medication was withdrawn. The proposal made use of the HDFP hypertensive population who had five years of treatment for their hypertension. Additionally, the group of investigators proposed to determine if dietary treatment would permit patients not previously adequately controlled under the HDFP program to achieve normalization of blood pressure with a combination of dietary modification and drug treatment. The study also proposed to search for predictors (i.e., levels of hormonal agents such as plasma renin activity) of responsiveness to dietary manipulation among the hypertensive population as well as to identify psychological attributes that might be of importance in managing these patients.
CONDITIONS
Official Title
Dietary Intervention Study for Hypertension (DISH)
Who Can Participate
Age: 40Years +
All Genders
Eligibility Criteria
You may qualify if you...
Men and women with hypertension. Diastolic blood pressure equal to or above 95 mm Hg and 90 mm Hg, respectively for home and clinic readings.
You will not qualify if you...
History of severe allergic reactions to study medication Currently pregnant or breastfeeding Recent participation in another clinical trial within the last 30 days Presence of uncontrolled medical conditions that could affect safety
Trial Site Locations
Site Locations not provided
Location information for this trial is currently unavailable.
How is the study designed?
Study Type
INTERVENTIONAL
Masking
N/A
Allocation
RANDOMIZED
Model
N/A
Primary Purpose
TREATMENT
Number of Arms
0
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Published Research Related To This Trial
Dietary approaches to the reduction of blood pressure: the independence of weight and sodium/potassium interventions.
R R Wing, A W Caggiula, M P Nowalk...
https://pubmed.ncbi.nlm.nih.gov/6494106Dietary therapy slows the return of hypertension after stopping prolonged medication.
H G Langford, M D Blaufox, A Oberman...
https://pubmed.ncbi.nlm.nih.gov/3881608Sodium restriction in hypertension.
H G Langford, D Schlundt, K Levine
https://pubmed.ncbi.nlm.nih.gov/6488753