Actively Recruiting

Age: 18Years +
All Genders
ID05767619

Development of a Decision Support System in the Assessment of Patients With Chest Pain in the Prehospital Setting

Led by Vastra Gotaland Region · Updated on 2023-06-18

2000

Participants Needed

3

Research Sites

104 weeks

Total Duration

On this page

Sponsors

V

Vastra Gotaland Region

Lead Sponsor

D

Department of Prehospital Emergency Care, Region Halland, Sweden

Collaborating Sponsor

AI-Summary

What this Trial Is About

This research aims to develop and improve a decision support system for patients experiencing chest pain before they reach the hospital. It focuses on evaluating how well a machine learning model can assist emergency medical services in assessing these patients. The study addresses the challenge of safely directing patients to the right level of care, balancing timely treatment for serious conditions like heart attacks or strokes with avoiding unnecessary hospital visits that may cause delays or overcrowding. Participants will be asked questions at the scene about their medical history and pain details, and a blood sample for troponin and glucose will be taken and analyzed immediately. The study collects routine medical record data and scene measurements to validate and further develop the decision support model. Participants will continue to receive standard care according to guidelines, typically transport to an emergency department if needed. Throughout the study, researchers will monitor clinical outcomes including time-sensitive conditions, deaths within seven days, and adverse events within 72 hours after ambulance service inclusion. Data from the initial assessment, blood tests, and medical records will help evaluate the model's predictive performance. The study is observational, and participant involvement includes answering questions and consenting to data and sample collection. The total duration extends from emergency contact through hospital discharge and follow-up periods up to 100 days.

CONDITIONS

Brief Title

Digital Decision Support in the Management of Patients With Chest Pain

Who Can Participate

Age: 18Years +
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Patient in contact with emergency medical services with chest pain or chest discomfort as the main symptom
  • This is the patient's primary assignment, not previously assessed by a physician in primary care or hospital
  • Age 18 years or older
Not Eligible

You will not qualify if you...

  • Assignment occurs outside the geographical area of the participating emergency medical service organization
  • Younger than 18 years old
  • Unwilling to participate
  • Unable to participate due to language barriers, dementia, or similar reasons
  • Other reasons preventing participation

AI-Screening

AI-Powered Screening

Complete this quick 3-step screening to check your eligibility

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

Diagnostic Evaluation

Duration - Single time point at emergency assessment

Participants have blood samples taken at the scene including Troponin (hs-cTnI) and plasma glucose measurements.

1 visit (in-person) at the scene of the illness

Long-term Monitoring

Duration - Up to 100 days after emergency medical service inclusion

Participants are observed for clinical outcomes including time-sensitive conditions, adverse events, and death following the initial assessment and standard care.

Trial Site Locations

Total: 3 locations

1

Department of Prehospital Emergency Care,Region Halland

Kungsbacka, Region Halland, Sweden

Actively Recruiting

2

Department of Prehospital Emergency Care, Sahlgrenska University Hospital

Gothenburg, Region Vastra Gotaland, Sweden, 41104

Actively Recruiting

3

Department of Prehospital Emergency Care, Skaraborg

Lidköping, Region Vastra Gotaland, Sweden

Actively Recruiting

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Research Team

C

Carl Magnusson, PhD,RN

K

Kristoffer Wibring, PhD,RN

How is the study designed?

Study Type

OBSERVATIONAL

Masking

N/A

Allocation

N/A

Model

N/A

Primary Purpose

N/A

Number of Arms

0

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Published Research Related To This Trial

The development of a decision support tool in the prehospital setting for acute chest pain - a study protocol for an observational study (BRIAN2).

Elin Lökholm, Carl Magnusson, Johan Herlitz...

https://pubmed.ncbi.nlm.nih.gov/39762958