The development of a decision support tool in the prehospital setting for acute chest pain - a study protocol for an observational study (BRIAN2).
Elin Lökholm, Carl Magnusson, Johan Herlitz...
https://pubmed.ncbi.nlm.nih.gov/39762958Actively Recruiting
Led by Vastra Gotaland Region · Updated on 2023-06-18
2000
Participants Needed
3
Research Sites
104 weeks
Total Duration
V
Vastra Gotaland Region
Lead Sponsor
D
Department of Prehospital Emergency Care, Region Halland, Sweden
Collaborating Sponsor
This research aims to develop and improve a decision support system for patients experiencing chest pain before they reach the hospital. It focuses on evaluating how well a machine learning model can assist emergency medical services in assessing these patients. The study addresses the challenge of safely directing patients to the right level of care, balancing timely treatment for serious conditions like heart attacks or strokes with avoiding unnecessary hospital visits that may cause delays or overcrowding. Participants will be asked questions at the scene about their medical history and pain details, and a blood sample for troponin and glucose will be taken and analyzed immediately. The study collects routine medical record data and scene measurements to validate and further develop the decision support model. Participants will continue to receive standard care according to guidelines, typically transport to an emergency department if needed. Throughout the study, researchers will monitor clinical outcomes including time-sensitive conditions, deaths within seven days, and adverse events within 72 hours after ambulance service inclusion. Data from the initial assessment, blood tests, and medical records will help evaluate the model's predictive performance. The study is observational, and participant involvement includes answering questions and consenting to data and sample collection. The total duration extends from emergency contact through hospital discharge and follow-up periods up to 100 days.
CONDITIONS
Digital Decision Support in the Management of Patients With Chest Pain
You may qualify if you...
You will not qualify if you...
Complete this quick 3-step screening to check your eligibility
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
Duration - Single time point at emergency assessment
Participants have blood samples taken at the scene including Troponin (hs-cTnI) and plasma glucose measurements.
1 visit (in-person) at the scene of the illness
Duration - Up to 100 days after emergency medical service inclusion
Participants are observed for clinical outcomes including time-sensitive conditions, adverse events, and death following the initial assessment and standard care.
Total: 3 locations
1
Department of Prehospital Emergency Care,Region Halland
Kungsbacka, Region Halland, Sweden
Actively Recruiting
2
Department of Prehospital Emergency Care, Sahlgrenska University Hospital
Gothenburg, Region Vastra Gotaland, Sweden, 41104
Actively Recruiting
3
Department of Prehospital Emergency Care, Skaraborg
Lidköping, Region Vastra Gotaland, Sweden
Actively Recruiting
C
Carl Magnusson, PhD,RN
K
Kristoffer Wibring, PhD,RN
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
0
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Elin Lökholm, Carl Magnusson, Johan Herlitz...
https://pubmed.ncbi.nlm.nih.gov/39762958