Actively Recruiting

Phase Not Applicable
Age: 25Years - 39Years
All Genders
ID06172907

A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers

Led by Massachusetts General Hospital · Updated on 2026-01-12

20

Participants Needed

4

Research Sites

26 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Young adults aged 25 to 39 who have cancer face unique challenges in coping, and their partners who provide care may feel burdened and less confident in their caregiving roles. Researchers are evaluating a brief psychotherapy intervention designed to improve how these young adults and their caregiving partners cope with cancer and maintain their relationships. This pilot study aims to test whether this intervention is feasible and acceptable in this specific group, providing important information for future larger studies. The intervention involves eight weekly virtual psychotherapy sessions lasting 45 to 60 minutes, delivered to young adults with cancer and their self-identified partners together. It is based on cognitive-behavioral therapy and couples-focused therapy principles tailored for young adults. A trained mental health practitioner will guide the sessions, which include teaching, practical exercises, and home practice. The study includes 10 young adults with cancer and their caregiving partners, totaling 20 participants. Participants will complete surveys before starting the intervention and again after finishing the eight sessions to measure feasibility and acceptability over approximately 14 weeks. They will also be invited to take part in optional interviews to share their experiences. This study is sponsored by Massachusetts General Hospital and does not include a control group or blinding. The total duration of involvement for participants is about three and a half months.

CONDITIONS

Brief Title

A Dyadic Intervention for Young Adult Patients With Cancer and Their Partner Caregivers

Who Can Participate

Age: 25Years - 39Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • Currently receiving active cancer treatment or within two years of completing treatment at Massachusetts General Cancer Center for young adults aged 25-39
  • Partner of an individual aged 25-39 currently receiving or within two years of completing cancer treatment at the same center
  • Distress score of 4 or higher on the NCCN adapted distress thermometer screening
  • English-speaking
Not Eligible

You will not qualify if you...

  • Uncontrolled psychosis
  • Active suicidal thoughts
  • Cognitive impairment

AI-Screening

AI-Powered Screening

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Your Study Journey

Screening

Duration - 2 to 4 weeks

Participants are screened for eligibility to participate in the trial.

1 visit (virtual or in-person)

Outpatient Treatment

Duration - 8 weeks

Participants attend eight weekly virtual dyadic psychotherapy sessions focusing on coping with cancer and caregiving using cognitive-behavioral and couples therapy techniques.

8 weekly virtual sessions

Follow-up

Duration - Approximately 4 weeks after intervention

Participants complete surveys and may choose to participate in optional semi-structured exit interviews to assess the intervention's feasibility and acceptability.

1 follow-up survey and optional interview

Trial Site Locations

Total: 4 locations

1

Massachusetts General Hospital Cancer Center

Boston, Massachusetts, United States, 02114

Actively Recruiting

2

Emerson Hospital/MGH Cancer Center

Concord, Massachusetts, United States, 01742

Actively Recruiting

3

Mass General at North Shore Cancer Center

Danvers, Massachusetts, United States, 01923

Actively Recruiting

4

Mass General at Newton Wellesley Hospital

Newton, Massachusetts, United States, 02462

Actively Recruiting

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Research Team

J

Jamie M Jacobs, Ph.D.

Z

Zeba N Ahmad, Ph.D.

How is the study designed?

Study Type

INTERVENTIONAL

Masking

NONE

Allocation

NA

Model

SINGLE_GROUP

Primary Purpose

SUPPORTIVE_CARE

Number of Arms

1

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