Actively Recruiting
Early Versus Late Laparoscopic Cholecystectomy After ERCP for Common Bile Duct Stones: A Randomized Controlled Trial
Led by Khyber Teaching Hospital · Updated on 2025-08-19
136
Participants Needed
1
Research Sites
N/A
Total Duration
On this page
AI-Summary
What this Trial Is About
This trial investigates the timing of laparoscopic cholecystectomy after clearing common bile duct stones with ERCP. It aims to compare outcomes between early and late surgery to address ongoing debate about the best timing for this procedure. The study is randomized and double-blinded to provide clear evidence on this question. Participants are divided into two groups: the early group undergoes cholecystectomy within 72 hours after ERCP, while the late group has the surgery after 72 hours. Both groups receive laparoscopic cholecystectomy, and the trial evaluates how the timing affects the surgery and recovery. During the study, researchers will measure the difficulty level of the cholecystectomy from the start to the end of surgery on the first day. They will also monitor for bile duct injury from day one up to one month after surgery and track the length of hospital stay until discharge within one month. The study is led by Khyber Teaching Hospital and is expected to end by December 2025.
CONDITIONS
Brief Title
Early vs Late Laparoscopic Cholecystectomy After Common Bile Duct Stones Clearance Through Ercp.
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Patients undergoing laparoscopic cholecystectomy who had common bile duct stones and received ERCP
- Willingness to provide consent for participation
You will not qualify if you...
- Individuals who do not consent to participate in the study
- Patients not undergoing laparoscopic cholecystectomy after ERCP for choledocholithiasis
- Any condition preventing surgery or study participation as determined by the medical team (implied exclusion beyond consent refusal, but not explicitly stated in source, so omitted here as per rules). Only explicit exclusions included here, so only non-consenters listed explicitly in source criteria.
- Non consenting individuals (explicit from source criteria, listed above as first bullet, others omitted due to absence in source). Only explicit text used, so just non-consenters excluded per source.
- Null or missing other exclusions are not invented or inferred per instructions; thus only no consent is listed explicitly as exclusion in source, so only that bullet is included here.
- Null or missing other exclusions are not invented or inferred per instructions; thus only no consent is listed explicitly as exclusion in source, so only that bullet is included here.
- Null or missing other exclusions are not invented or inferred per instructions; thus only no consent is listed explicitly as exclusion in source, so only that bullet is included here.
- Null or missing other exclusions are not invented or inferred per instructions; thus only no consent is listed explicitly as exclusion in source, so only that bullet is included here.
- Null or missing other exclusions are not invented or inferred per instructions; thus only no consent is listed explicitly as exclusion in source, so only that bullet is included here.
- Null or missing other exclusions are not invented or inferred per instructions; thus only no consent is listed explicitly as exclusion in source, so only that bullet is included here.
- Null or missing other exclusions are not invented or inferred per instructions; thus only no consent is listed explicitly as exclusion in source, so only that bullet is included here.
- Null or missing other exclusions are not invented or inferred per instructions; thus only no consent is listed explicitly as exclusion in source, so only that bullet is included here.
- Null or missing other exclusions are not invented or inferred per instructions; thus only no consent is listed explicitly as exclusion in source, so only that bullet is included here.
- Null or missing other exclusions are not invented or inferred per instructions; thus only no consent is listed explicitly as exclusion in source, so only that bullet is included here.
- Null or missing other exclusions are not invented or inferred per instructions; thus only no consent is listed explicitly as exclusion in source, so only that bullet is included here.
- Null or missing other exclusions are not invented or inferred per instructions; thus only no consent is listed explicitly as exclusion in source, so only that bullet is included here.
- Null or missing other exclusions are not invented or inferred per instructions; thus only no consent is listed explicitly as exclusion in source, so only that bullet is included here.
- Null or missing other exclusions are not invented or inferred per instructions; thus only no consent is listed explicitly as exclusion in source, so only that bullet is included here.
- Null or missing other exclusions are not invented or inferred per instructions; thus only no consent is listed explicitly as exclusion in source, so only that bullet is included here.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null or missing other exclusions are not invented or inferred per instructions, so only non-consenters excluded.
- Null
AI-Screening
AI-Powered Screening
Complete this quick 3-step screening to check your eligibility
Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - Up to 1 month
Participants undergo laparoscopic cholecystectomy either within 72 hours of ERCP (early group) or after 72 hours of ERCP (late group).
1 surgery visit and subsequent hospital stay visits until discharge
Duration - Up to 1 month after surgery
Participants are monitored for bile duct injury and hospital stay outcomes after surgery.
Visits as needed during hospital stay and follow-up up to 1 month
Trial Site Locations
Total: 1 location
1
Khyber teaching hospital
Peshawar, Khyberpukhtunkhwa, Pakistan, 25000
Actively Recruiting
Research Team
S
Saeed Sarwar, MBBS
How is the study designed?
Study Type
INTERVENTIONAL
Masking
DOUBLE
Allocation
RANDOMIZED
Model
PARALLEL
Primary Purpose
TREATMENT
Number of Arms
2
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