Evaluating an Anti-inflammatory Diets Effects on Symptoms and Biomarkers in Adults with Systemic Lupus Erythematosus

What this Trial Is About

Researchers are evaluating the effects of an anti-inflammatory diet on adults with Systemic Lupus Erythematosus SLE. The study aims to understand how inflammation and related molecules, as well as gut bacteria, change in people with lupus. This exploratory trial is designed to generate early data on how dietary changes might influence blood biomarkers and the gut microbiome, potentially offering insights into lupus mechanisms and future treatments. Participants will follow an anti-inflammatory diet for six weeks. Blood and stool samples will be collected and analyzed to compare biological changes before and after the dietary intervention. The study focuses on short-term effects and does not involve other treatment comparisons. During the six-week period, participants will be assessed for changes in symptoms such as pain interference and fatigue using the PROMIS scales. Researchers will also evaluate physical function. Participants will provide biological samples for laboratory analysis, and their adherence to the diet will be monitored. The entire study participation lasts at least six weeks, with measurements taken to understand the diets impact on lupus symptoms and biomarkers.

Effect of Anti-inflammatory Diet in Systemic Lupus Erythematous