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Actively Recruiting

Phase Not Applicable
Age: 18Years - 65Years
All Genders
ID07608861

Comparing Timing of Bilateral Maxillary Nerve Block to Reduce Pain and Opioid Use During Septorhinoplasty Surgery

Led by Atatürk Chest Diseases and Chest Surgery Training and Research Hospital · Updated on 2026-06-02

80

Participants Needed

1

Research Sites

2 weeks

Total Duration

On this page

AI-Summary

What this Trial Is About

Researchers are evaluating the effects of the timing of bilateral maxillary nerve block administration on intraoperative remifentanil use and postoperative pain control in patients undergoing septorhinoplasty surgery. This regional anesthetic technique targets the maxillary nerve to provide pain relief during and after midfacial and maxillary surgeries. The study compares administering the block after intubation versus before extubation to assess impacts on opioid consumption and pain management. Participants will be randomly assigned to receive the maxillary nerve block either after intubation or before extubation. The block is performed under ultrasound guidance using an infrazygomatic approach to access the pterygopalatine fossa. Each side receives 4 mL of a local anesthetic solution consisting of 2 mL of 0.5% bupivacaine and 2 mL of 2% lidocaine. The procedure involves visualization of anatomical landmarks and careful injection to ensure proper delivery. During the study, researchers will monitor intraoperative remifentanil consumption, mean arterial pressure, heart rate, and postoperative pain scores within the first 24 hours after surgery. The block procedure preparation includes aseptic techniques and the use of ultrasound imaging. Participation involves standard surgical care with added nerve block administration and close monitoring of vital signs and pain levels to evaluate the effects of the timing of the block.

CONDITIONS

Brief Title

Effect of Bilateral Maxillary Block on Intraoperative Remifentanil Consumption

Who Can Participate

Age: 18Years - 65Years
All Genders

Eligibility Criteria

Eligible

You may qualify if you...

  • 18 to 65 years old
  • American Society of Anesthesiologists (ASA) physical status I-II
  • Body mass index between 18 and 30 kg/m2
  • Scheduled for septorhinoplasty surgery
Not Eligible

You will not qualify if you...

  • Refusal to undergo the nerve block procedure
  • Previous nasal surgery
  • Chronic use of opioids or other analgesics
  • Allergies to local anesthetics
  • Hypertension or receiving antihypertensive treatment

Research Team

M

Musa Zengin, Associate Professor

M

Mücahit Yılmaz, Medical Doctor

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