Actively Recruiting
Effect of Different Meal Types Given Before Exercise on Plasma Amino Acid Levels and Metabolic Control Parameters in Classical Phenylketonuria Patients Undergoing Aerobic and Resistance Exercises
Led by Hacettepe University · Updated on 2026-04-16
10
Participants Needed
1
Research Sites
41 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
This study will be the first in the literature to evaluate the relationship between aerobic and resistance exercises, plasma amino acid levels, metabolic control of patients, and the metabolic response to exercise with different types of meals in patients with Phenylketonuria (PKU). In patients with phenylketonuria, the aim is to determine which pre-exercise dietary recommendations are more physiologically appropriate and ideal for achieving good metabolic control. In the literature, there are very few studies examining the effects of exercise on plasma amino acid levels and metabolic parameters in PKU patients.
CONDITIONS
Official Title
Effect of Different Meal Types Given Before Exercise on Plasma Amino Acid Levels and Metabolic Control Parameters in Classical Phenylketonuria Patients Undergoing Aerobic and Resistance Exercises
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Be over 18 years old,
- Having a classic FKU diagnosis,
- Not being actively engaged in sports,
- Not having any other existing diseases,
- Not having an active infection,
- Have a BMI in the range of 20-28 kg/m2 within the last 3 months,
- Agreeing to consume test meals and provide blood samples for parameters that will evaluate plasma amino acid levels as part of the research
- Being willing to participate in this study
You will not qualify if you...
- Presence of a chronic disease accompanying FKU disease (endocrine, etc.)
- The individual with FKU has mental retardation or is deemed unfit for work based on psychomotor assessment,
- Recent weight loss, history of hospitalisation, a past infection, or a diagnosed illness
- Use of drugs or alcohol that alter protein and energy metabolism (e.g., corticosteroids, etc.)
- Pregnancy status
- Smoking habits The considerations to be taken into account when planning the day/date of the test are as follows.
- Having engaged in heavy exercise or sports within 24 hours before the application of test diets,
- Being in the menstrual period for female patients.
AI-Screening
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Trial Site Locations
Total: 1 location
1
Hacettepe University
Ankara, Ankara, Turkey (Türkiye), 06100
Actively Recruiting
Research Team
D
DAMLA KALKAN, MSc, PhD(c)
CONTACT
How is the study designed?
Study Type
INTERVENTIONAL
Masking
NONE
Allocation
RANDOMIZED
Model
CROSSOVER
Primary Purpose
OTHER
Number of Arms
6
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