Actively Recruiting
Effect of Graft Type on Knee Muscle Strength Development After Anterior Cruciate Ligament Reconstruction
Led by Hacettepe University · Updated on 2026-04-15
80
Participants Needed
1
Research Sites
4 weeks
Total Duration
On this page
AI-Summary
What this Trial Is About
Researchers are comparing recovery after anterior cruciate ligament (ACL) reconstruction using two types of tendon grafts: quadriceps tendon autograft and hamstring tendon autograft. The study focuses on differences in knee muscle strength recovery during the early and mid-term periods after surgery. It includes participants aged 13 to 45 years who undergo unilateral ACL reconstruction and have a certain activity level. The aim is to better understand how graft type may affect muscle strength and function after surgery. Participants are divided into two groups based on the type of tendon graft used in their ACL reconstruction. Both groups follow the same standardized rehabilitation program supervised by a physiotherapist twice a week for 12 weeks, along with home exercises. Muscle strength is tested using specific machines at various time points after surgery, including weeks 4, 8, and 12, and months 3 and 6. Functional outcomes and fear of movement are assessed at 6 months using validated questionnaires. During the study, participants will have strength tests measuring quadriceps and hamstring muscles, along with surveys on knee function and movement fears. These tests occur at set intervals up to 6 months after surgery. The research team will monitor progress and any discomfort during rehabilitation and testing. The main goal is to compare muscle strength recovery and functional improvement between the two graft groups, providing insight into the impact of graft choice on ACL recovery.
CONDITIONS
Brief Title
Effect of Graft Type on Knee Muscle Strength After ACL Reconstruction
Who Can Participate
Eligibility Criteria
You may qualify if you...
- Age 13 to 45 years
- Undergoing anterior cruciate ligament reconstruction with either hamstring tendon autograft or quadriceps tendon autograft
- Unilateral anterior cruciate ligament injury
- Complete ACL tear with minimal collateral ligament injury and first-degree meniscal tear
- Tegner Activity Score of 5 or higher
- Willingness to participate in the study
You will not qualify if you...
- Anterior cruciate ligament reconstruction with patellar tendon autograft or allograft
- Revision surgery
- Systemic or neurological disease
- Multiple ligament injuries
- Grade III lateral or medial collateral ligament tear or significant articular cartilage lesion
- Failure to regularly attend the rehabilitation program during the first 3 postoperative months
- History of lower extremity injury in the contralateral limb within the last 12 months
- Hypertension, cardiovascular disease, peripheral vascular disease, history of deep vein thrombosis, neurological disease, systemic inflammation, diabetes, cancer, or obesity
AI-Screening
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Your Study Journey
Duration - 2 to 4 weeks
Participants are screened for eligibility to participate in the trial.
1 visit (in-person)
Duration - 12 weeks
Participants who undergo routine anterior cruciate ligament reconstruction with either quadriceps tendon or hamstring tendon autografts are followed prospectively while participating in a standardized postoperative rehabilitation program.
Twice weekly physiotherapy visits plus home exercise program
Duration - 6 months
Participants are assessed for knee muscle strength and functional outcomes at scheduled postoperative timepoints.
Strength testing at weeks 4, 8, and 12, and months 3 and 6; functional assessments at month 6
Trial Site Locations
Total: 1 location
1
Hacettepe University
Ankara, Turkey (Türkiye), 06100
Actively Recruiting
Research Team
V
Volga Bayrakci Tunay Bayrakci Tunay, Phd
How is the study designed?
Study Type
OBSERVATIONAL
Masking
N/A
Allocation
N/A
Model
N/A
Primary Purpose
N/A
Number of Arms
2
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