Impact of Personalized Exercise Training on Heart and Lung Function in Older Adults with Coronary Heart Disease Aged 60 to 75

What this Trial Is About

Researchers are studying elderly patients aged 60 to 75 years who have coronary heart disease confirmed by coronary angiography and stable sinus rhythm. The study evaluates the effects of individualized exercise rehabilitation on cardiovascular risk factors and cardiopulmonary function. Cardiac rehabilitation, recommended by major heart associations, combines drug therapy, exercise, nutrition, psychological and behavioral support, and lifestyle changes to improve symptoms, prognosis, and quality of life in patients with heart disease. The study compares two groups a control group receiving routine rehabilitation nursing, antiplatelet drugs, lipid-lowering drugs, and dietary guidance, and an exercise group receiving the same medical treatment plus individualized rehabilitation exercise training. The exercise involves medium- to high-intensity interval training three times a week for 16 weeks, with sessions lasting 30 to 40 minutes including warm-up and cool-down periods, tailored to each patients physical condition. Participants will be monitored for one year, with assessments including gut microbiome analysis, plasma metabolite profiles, walking distance tests 6-minute walk test, LDL cholesterol levels, and peak oxygen uptake VO2peak. Researchers will track physical, psychological, and social functions, and evaluate how the exercise intervention influences cardiovascular risk and heart and lung function. This comprehensive follow-up aims to understand long-term benefits and safety of the rehabilitation program.

Effect of Individualized Exercise in Elderly Patients With Coronary Heart Disease